Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934745 | 1.00 | DPP4 (0.67) | DPP4KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL2934742 | 1.00 | DPP4 (0.67) | DPP4KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL4470335 | 0.88 | DPP4 (0.53) | DPP4KMT2AALDH1A1FPR1FPR2 | |
| SCHEMBL4470342 | 0.88 | DPP4 (0.53) | DPP4KMT2AALDH1A1FPR1FPR2 | |
| SCHEMBL4470331 | 0.88 | DPP4 (0.53) | DPP4KMT2AALDH1A1FPR1FPR2 | |
| SCHEMBL1243424 | 0.83 | DPP4 (0.71) | DPP4KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1243419 | 0.83 | DPP4 (0.71) | DPP4KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1243422 | 0.83 | DPP4 (0.71) | DPP4KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1724899 | 0.82 | DPP4 (0.48) | DPP4KMT2A | |
| SCHEMBL5924067 | 0.82 | DPP4 (0.48) | DPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796669-B1 | AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME (US) | 2010-09-22 | — | — | EP | disclosed |