Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924067 | 1.00 | DPP4 (0.48) | DPP4SIGMAR1L3MBTL1GRIN2BSLC6A12 | |
| SCHEMBL1240975 | 0.91 | SIGMAR1 (0.51) | DPP4SIGMAR1L3MBTL1SLC6A12TMEM97 | |
| SCHEMBL5123894 | 0.91 | SIGMAR1 (0.51) | DPP4SIGMAR1L3MBTL1SLC6A12TMEM97 | |
| SCHEMBL470519 | 0.86 | DPP4 (0.48) | DPP4SIGMAR1GRIN2BDRD2DRD3 | |
| SCHEMBL147898 | 0.85 | L3MBTL1 (0.46) | DPP4SIGMAR1L3MBTL1DRD2DRD4 | |
| SCHEMBL147897 | 0.85 | L3MBTL1 (0.46) | DPP4SIGMAR1L3MBTL1DRD2DRD4 | |
| SCHEMBL147896 | 0.85 | L3MBTL1 (0.46) | DPP4SIGMAR1L3MBTL1DRD2DRD4 | |
| SCHEMBL2934745 | 0.82 | DPP4 (0.67) | DPP4KMT2A | |
| SCHEMBL2934740 | 0.82 | DPP4 (0.67) | DPP4KMT2A | |
| SCHEMBL2934742 | 0.82 | DPP4 (0.67) | DPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406251-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103334-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |