Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582903 | 0.89 | BACE1 (0.50) | ACKR3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL22036273 | 0.89 | MEN1 (0.53) | ACKR3KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21358915 | 0.89 | CCR3 (0.51) | ACKR3KMT2ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL4149104 | 0.89 | CCR3 (0.51) | ACKR3KMT2ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL8237687 | 0.89 | ACKR3 (0.57) | GPR119ACKR3KDM1AFEN1KAT7 | |
| SCHEMBL6214983 | 0.89 | ACKR3 (0.57) | GPR119ACKR3KDM1AFEN1KAT7 | |
| SCHEMBL15331285 | 0.87 | BACE1 (0.46) | ACKR3KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL29136138 | 0.87 | KMT2A (0.49) | ACKR3KMT2AMEN1KDM1AFEN1 | |
| SCHEMBL13503047 | 0.86 | GPR119 (0.54) | GPR119ACKR3MAPTKDM1AKAT7 | |
| SCHEMBL16113579 | 0.85 | GPR119 (0.61) | GPR119TP53KMT2AMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141757-A1 | LSD1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2024-07-04 | — | — | WO | disclosed |