Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 4/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348400 | 0.87 | CRBN (0.46) | CRBNDDB1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29348431 | 0.86 | CRBN (0.40) | PDE10ACRBNDDB1BRD4CREBBP | |
| SCHEMBL29348398 | 0.86 | CRBN (0.41) | CRBNDDB1BRD4CREBBP | |
| SCHEMBL29348356 | 0.85 | CRBN (0.44) | CRBNDDB1BRD4CREBBP | |
| SCHEMBL29348571 | 0.85 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL31068173 | 0.85 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL29348577 | 0.84 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL31068109 | 0.83 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL31068149 | 0.83 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL29348414 | 0.83 | CRBN (0.46) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |