Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068173 | 1.00 | CRBN (0.46) | CRBNDDB1LTA4HPTGS2BACE1 | |
| SCHEMBL29348577 | 0.89 | CRBN (0.44) | CRBNDDB1POLB | |
| SCHEMBL29348338 | 0.85 | PDE10A (0.48) | CRBNDDB1 | |
| SCHEMBL31068208 | 0.84 | CRBN (0.43) | CRBNDDB1POLB | |
| SCHEMBL29348396 | 0.84 | CRBN (0.43) | CRBNDDB1POLB | |
| SCHEMBL38660589 | 0.81 | CRBN (0.39) | CRBNDDB1 | |
| SCHEMBL31068241 | 0.81 | DDB1 (0.56) | CRBNDDB1 | |
| SCHEMBL29348441 | 0.80 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL29348356 | 0.80 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL29348400 | 0.80 | CRBN (0.46) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |