8-Azaguanine

8-Azaguanine

SCHEMBL2934836

Nc1nc(O)c2[nH]nnc2n1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.31
GDA Q9Y2T3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31561489 0.78 PDPK1 (0.45) PDPK1GDA
SCHEMBL4259327 0.75
SCHEMBL4052700 0.75 DPP4 (0.48) PDPK1GDA
SCHEMBL9168849 0.73
Sulfuric Acid SCHEMBL3317386 0.73 PDPK1 (0.38) PDPK1GDA
SCHEMBL10516335 0.72
8-Aminoguanine SCHEMBL27531531 0.68 PNP (0.48) PDPK1GDA
SCHEMBL6481197 0.68 NUDT1 (0.35) PDPK1GDA
8-Azaguanine SCHEMBL2934835 0.67
SCHEMBL7618859 0.65 PRKACA (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238519-C Process for producing nucleoside compound MITSUI CHEMICALS INC (JP) 2006-01-25 CN claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-2599865-B1 ANTI-FDP MONOCLONAL ANTIBODY, FDP MEASUREMENT REAGENT AND REAGENT KIT USING SAME, AND FDP MEASUREMENT METHOD SYSMEX CORP (JP) 2017-09-27 EP disclosed
US-8865424-B2 Anti-FDP monoclonal antibody, FDP measurement reagent and reagent kit using same, and FDP measurement method SYSMEX CORPORATION (JP) 2014-10-21 US disclosed
US-20130149793-A1 ANTI-FDP MONOCLONAL ANTIBODY, FDP MEASUREMENT REAGENT AND REAGENT KIT USING SAME, AND FDP MEASUREMENT METHOD SYSMEX CORPORATION (JP) 2013-06-13 US disclosed
EP-2599865-A1 ANTI-FDP MONOCLONAL ANTIBODY, FDP MEASUREMENT REAGENT AND REAGENT KIT USING SAME, AND FDP MEASUREMENT METHOD Sysmex Corporation (JP) 2013-06-05 EP disclosed
EP-1925675-B1 Process for production of nucleoside compound MITSUI CHEMICALS INC (JP) 2010-02-03 EP disclosed
EP-1338654-B1 PROCESS FOR PRODUCING NUCLEOSIDE COMPOUND MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
US-7381820-B2 α-1-phosphorylated-2-deoxy-2-fluoroarabinoside and process for producing 2′-deoxy-2′-fluoro-β-d-arabinonucleoside YAMASA CORPORATION (JP) 2008-06-03 US disclosed
EP-1178051-B1 PROCESS FOR SELECTIVELY PRODUCING 1-PHOSPHORYLATED SUGAR DERIVATIVE ANOMER AND PROCESS FOR PRODUCING NUCLEOSIDE MITSUI CHEMICALS INC (JP) 2008-05-28 EP disclosed
EP-1925675-A1 Process for production of nucleoside compound Mitsui Chemicals, Inc. (JP) 2008-05-28 EP disclosed
EP-0839813-A1 9-(2-DEOXY-2-FLUORO-4-THIO-BETA-D-ARABINOFURANOSYL)PURINE DERIVATIVES YAMASA CORPORATION (JP) 1998-05-06 EP disclosed
EP-0755255-A1 TREATMENT OF TOXOPLASMOSIS UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) 1997-01-29 EP disclosed
EP-0741144-A1 ANTIANNEXIN-V MONOCLONAL ANTIBODY, PROCESS FOR PRODUCING THE SAME, AND USE THEROF INTERNATIONAL REAGENTS CORPORATION (JP) 1996-11-06 EP disclosed
WO-1996018398-A1 TREATMENT OF TOXOPLASMOSIS THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) 1996-06-20 WO disclosed
US-5457091-A N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-10 US disclosed
EP-0589335-A1 N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-30 EP disclosed
EP-0298467-A2 2-Amino-8-aza purines substituted in positions 6 and 9, their use, medicaments containing these purines and process for the preparation of the purines HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-11 EP disclosed
US-4360663-A Steroid hormone-antitumor derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-11-23 US disclosed
US-4260736-A NAPHTHACENE HEXAPYRANOSIDE DERIVATIVE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-04-07 US disclosed