8-Azaguanine

8-Azaguanine

SCHEMBL2934836

Nc1nc(O)c2[nH]nnc2n1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PDPK1 O15530 1/20 0.31
▸ GDA Q9Y2T3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31561489 0.78 PDPK1 (0.45) PDPK1GDA
SCHEMBL4259327 0.75 — —
SCHEMBL4052700 0.75 DPP4 (0.48) PDPK1GDA
SCHEMBL9168849 0.73 — —
Sulfuric Acid SCHEMBL3317386 0.73 PDPK1 (0.38) PDPK1GDA
SCHEMBL10516335 0.72 — —
SCHEMBL6481197 0.68 NUDT1 (0.35) PDPK1GDA
8-Aminoguanine SCHEMBL27531531 0.68 PNP (0.48) PDPK1GDA
8-Azaguanine SCHEMBL2934835 0.67 — —
SCHEMBL7618859 0.65 PRKACA (0.44) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238519-C Process for producing nucleoside compound MITSUI CHEMICALS INC (JP) 2006-01-25 — — CN claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 — — EP claimed
EP-2599865-B1 ANTI-FDP MONOCLONAL ANTIBODY, FDP MEASUREMENT REAGENT AND REAGENT KIT USING SAME, AND FDP MEASUREMENT METHOD SYSMEX CORP (JP) 2017-09-27 — — EP disclosed
US-8865424-B2 Anti-FDP monoclonal antibody, FDP measurement reagent and reagent kit using same, and FDP measurement method SYSMEX CORPORATION (JP) 2014-10-21 — — US disclosed
US-20130149793-A1 ANTI-FDP MONOCLONAL ANTIBODY, FDP MEASUREMENT REAGENT AND REAGENT KIT USING SAME, AND FDP MEASUREMENT METHOD SYSMEX CORPORATION (JP) 2013-06-13 — — US disclosed
EP-2599865-A1 ANTI-FDP MONOCLONAL ANTIBODY, FDP MEASUREMENT REAGENT AND REAGENT KIT USING SAME, AND FDP MEASUREMENT METHOD Sysmex Corporation (JP) 2013-06-05 — — EP disclosed
EP-1925675-B1 Process for production of nucleoside compound MITSUI CHEMICALS INC (JP) 2010-02-03 — — EP disclosed
EP-1338654-B1 PROCESS FOR PRODUCING NUCLEOSIDE COMPOUND MITSUI CHEMICALS INC (JP) 2008-10-15 — — EP disclosed
US-7381820-B2 α-1-phosphorylated-2-deoxy-2-fluoroarabinoside and process for producing 2′-deoxy-2′-fluoro-β-d-arabinonucleoside YAMASA CORPORATION (JP) 2008-06-03 — — US disclosed
EP-1178051-B1 PROCESS FOR SELECTIVELY PRODUCING 1-PHOSPHORYLATED SUGAR DERIVATIVE ANOMER AND PROCESS FOR PRODUCING NUCLEOSIDE MITSUI CHEMICALS INC (JP) 2008-05-28 — — EP disclosed
EP-1925675-A1 Process for production of nucleoside compound Mitsui Chemicals, Inc. (JP) 2008-05-28 — — EP disclosed
EP-0839813-A1 9-(2-DEOXY-2-FLUORO-4-THIO-BETA-D-ARABINOFURANOSYL)PURINE DERIVATIVES YAMASA CORPORATION (JP) 1998-05-06 — — EP disclosed
EP-0755255-A1 TREATMENT OF TOXOPLASMOSIS UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) 1997-01-29 — — EP disclosed
EP-0741144-A1 ANTIANNEXIN-V MONOCLONAL ANTIBODY, PROCESS FOR PRODUCING THE SAME, AND USE THEROF INTERNATIONAL REAGENTS CORPORATION (JP) 1996-11-06 — — EP disclosed
WO-1996018398-A1 TREATMENT OF TOXOPLASMOSIS THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) 1996-06-20 — — WO disclosed
US-5457091-A N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-10 — — US disclosed
EP-0589335-A1 N1-Substituted- (1H)-1,2,3-Triazolo (4,5-d) pyrimidines, process for their preparation and their use as antiviral means HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-30 — — EP disclosed
EP-0298467-A2 2-Amino-8-aza purines substituted in positions 6 and 9, their use, medicaments containing these purines and process for the preparation of the purines HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-11 — — EP disclosed
US-4360663-A Steroid hormone-antitumor derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-11-23 — — US disclosed
US-4260736-A NAPHTHACENE HEXAPYRANOSIDE DERIVATIVE KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-04-07 — — US disclosed
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