Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348370 | 0.86 | DDB1 (0.46) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL29348347 | 0.86 | CRBN (0.41) | CRBNDDB1PDCD1CD274 | |
| SCHEMBL29348371 | 0.85 | DDB1 (0.43) | CRBNDDB1BRD4PDCD1CD274 | |
| SCHEMBL29348340 | 0.84 | DDB1 (0.46) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL29348374 | 0.83 | DDB1 (0.46) | CRBNDDB1IKZF3 | |
| SCHEMBL29348363 | 0.82 | DDB1 (0.52) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL29348362 | 0.81 | CRBN (0.55) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL29348336 | 0.80 | CRBN (0.44) | CRBNDDB1TNFIL1BIKZF1 | |
| SCHEMBL31068241 | 0.78 | DDB1 (0.56) | CRBNDDB1IKZF3 | |
| SCHEMBL31068205 | 0.77 | DRD2 (0.43) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |