Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348357 | 0.78 | DDB1 (0.43) | CRBNDDB1POLBPDCD1LG2CD274 | |
| SCHEMBL29348364 | 0.75 | DDB1 (0.50) | CRBNDDB1PDCD1LG2CD274 | |
| SCHEMBL29348371 | 0.72 | DDB1 (0.43) | CRBNDDB1CD274 | |
| SCHEMBL29348358 | 0.71 | CRBN (0.50) | CRBNDDB1POLBPDCD1LG2CD274 | |
| SCHEMBL31068241 | 0.70 | DDB1 (0.56) | CRBNDDB1 | |
| SCHEMBL25575861 | 0.69 | DDB1 (0.66) | CRBNDDB1POLB | |
| SCHEMBL31068105 | 0.68 | DDB1 (0.56) | CRBNDDB1 | |
| SCHEMBL29348330 | 0.68 | DDB1 (0.56) | CRBNDDB1 | |
| SCHEMBL26049118 | 0.68 | DDB1 (0.73) | CRBNDDB1POLB | |
| SCHEMBL29348350 | 0.68 | CRBN (0.49) | CRBNDDB1POLBPDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |