Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348350 | 0.90 | CRBN (0.49) | CRBNDDB1POLBKMT2APDCD1LG2 | |
| SCHEMBL29348367 | 0.87 | CRBN (0.47) | CRBNDDB1POLBKMT2APDCD1LG2 | |
| SCHEMBL29348339 | 0.84 | CRBN (0.44) | CRBNDDB1KMT2APDCD1LG2CD274 | |
| SCHEMBL29348368 | 0.84 | TNF (0.49) | CRBNDDB1DRD2 | |
| SCHEMBL29348356 | 0.82 | CRBN (0.44) | CRBNDDB1PDCD1LG2CD274HTT | |
| SCHEMBL29348431 | 0.81 | CRBN (0.40) | CRBNDDB1POLBPDCD1LG2CD274 | |
| SCHEMBL29348338 | 0.81 | PDE10A (0.48) | CRBNDDB1 | |
| SCHEMBL29348577 | 0.80 | CRBN (0.44) | CRBNDDB1POLBPDCD1LG2CD274 | |
| SCHEMBL31068109 | 0.80 | CRBN (0.46) | CRBNDDB1PDCD1LG2CD274 | |
| SCHEMBL31068149 | 0.80 | CRBN (0.46) | CRBNDDB1PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |