Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068307 | 1.00 | DDB1 (0.45) | DDB1CRBNCD274PDCD1CNR2 | |
| SCHEMBL31068309 | 0.89 | DDB1 (0.47) | DDB1CRBNCD274PDCD1 | |
| SCHEMBL29348475 | 0.87 | DDB1 (0.43) | DDB1CRBNCD274PDCD1CNR2 | |
| SCHEMBL31068294 | 0.87 | DDB1 (0.43) | DDB1CRBNCD274PDCD1CNR2 | |
| SCHEMBL31068135 | 0.85 | CRBN (0.44) | DDB1CRBNCD274PDCD1PDCD1LG2 | |
| SCHEMBL29348677 | 0.85 | CRBN (0.44) | DDB1CRBNCD274PDCD1PDCD1LG2 | |
| SCHEMBL29348437 | 0.85 | CRBN (0.46) | DDB1CRBNCD274PDCD1PDCD1LG2 | |
| SCHEMBL31068109 | 0.85 | CRBN (0.46) | DDB1CRBNCD274PDCD1PDCD1LG2 | |
| SCHEMBL31068149 | 0.85 | CRBN (0.46) | DDB1CRBNCD274PDCD1PDCD1LG2 | |
| SCHEMBL29348386 | 0.85 | CRBN (0.46) | DDB1CRBNCD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |