SCHEMBL29348677 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CRBN	Q96SW2	16/20	0.44

▸	DDB1	Q16531	15/20	0.44

▸	CD274	Q9NZQ7	2/20	0.39

▸	PDCD1	Q15116	1/20	0.39

▸	ALOX5AP	P20292	1/20	0.34

▸	FEN1	P39748	1/20	0.34

▸	JAK2	O60674	1/20	0.34

▸	PDCD1LG2	Q9BQ51	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31068135	1.00	CRBN (0.44)	CRBNDDB1CD274PDCD1ALOX5AP
SCHEMBL29348475	0.90	DDB1 (0.43)	CRBNDDB1CD274PDCD1ALOX5AP
SCHEMBL31068294	0.90	DDB1 (0.43)	CRBNDDB1CD274PDCD1ALOX5AP
SCHEMBL31068109	0.90	CRBN (0.46)	CRBNDDB1CD274PDCD1JAK2
SCHEMBL29348386	0.90	CRBN (0.46)	CRBNDDB1CD274PDCD1JAK2
SCHEMBL29348437	0.90	CRBN (0.46)	CRBNDDB1CD274PDCD1JAK2
SCHEMBL31068149	0.90	CRBN (0.46)	CRBNDDB1CD274PDCD1JAK2
SCHEMBL29348439	0.90	CRBN (0.46)	CRBNDDB1CD274PDCD1JAK2
SCHEMBL31068307	0.85	DDB1 (0.45)	CRBNDDB1CD274PDCD1PDCD1LG2
SCHEMBL29348474	0.85	DDB1 (0.45)	CRBNDDB1CD274PDCD1PDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024151547-A1	TARGETED DEGRADATION OF VAV1	MONTE ROSA THERAPEUTICS, INC. (US)	2024-07-18	—	—	WO	disclosed