Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068362 | 1.00 | CNR2 (0.40) | CNR2DDB1CRBNALOX5APFEN1 | |
| SCHEMBL29348597 | 0.87 | DDB1 (0.40) | CNR2DDB1CRBNOPRM1OPRL1 | |
| SCHEMBL31068225 | 0.87 | DDB1 (0.40) | CNR2DDB1CRBNOPRM1OPRL1 | |
| SCHEMBL29348666 | 0.87 | ALOX5AP (0.37) | CNR2DDB1CRBNALOX5APFEN1 | |
| SCHEMBL29348867 | 0.85 | DDB1 (0.37) | CNR2DDB1CRBNIKZF3OPRM1 | |
| SCHEMBL29348994 | 0.84 | CNR2 (0.59) | CNR2DDB1CRBN | |
| SCHEMBL31068267 | 0.84 | CNR2 (0.59) | CNR2DDB1CRBN | |
| SCHEMBL31068144 | 0.83 | DDB1 (0.37) | CNR2DDB1CRBNIKZF3OPRM1 | |
| SCHEMBL29348582 | 0.83 | DDB1 (0.37) | CNR2DDB1CRBNIKZF3OPRM1 | |
| SCHEMBL31068230 | 0.83 | DDB1 (0.38) | DDB1CRBNIKZF3OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |