Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068144 | 1.00 | DDB1 (0.37) | DDB1CRBNOPRM1OPRL1PDCD1LG2 | |
| SCHEMBL29348581 | 0.97 | DDB1 (0.38) | DDB1CRBNOPRM1OPRL1PDCD1LG2 | |
| SCHEMBL31068230 | 0.97 | DDB1 (0.38) | DDB1CRBNOPRM1OPRL1PDCD1LG2 | |
| SCHEMBL29348867 | 0.95 | DDB1 (0.37) | DDB1CRBNOPRM1OPRL1PDCD1LG2 | |
| SCHEMBL31068275 | 0.84 | CNR2 (0.41) | DDB1CRBNCNR2 | |
| SCHEMBL29348607 | 0.84 | CNR2 (0.41) | DDB1CRBNCNR2 | |
| SCHEMBL29348585 | 0.83 | CNR2 (0.40) | DDB1CRBNOPRM1OPRL1PDCD1LG2 | |
| SCHEMBL31068362 | 0.83 | CNR2 (0.40) | DDB1CRBNOPRM1OPRL1PDCD1LG2 | |
| SCHEMBL29348869 | 0.82 | PDCD1LG2 (0.34) | OPRM1OPRL1PDCD1LG2CD274CNR2 | |
| SCHEMBL29348664 | 0.81 | DDB1 (0.40) | DDB1CRBNOPRM1ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |