⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158429 | 0.79 | — | — | |
| SCHEMBL299546 | 0.77 | — | — | |
| SCHEMBL299547 | 0.77 | — | — | |
| SCHEMBL167265 | 0.77 | HCAR2 (0.56) | — | |
| Diethyl Maleate SCHEMBL42602 | 0.77 | HCAR2 (0.80) | — | |
| Diethyl Maleate SCHEMBL2015895 | 0.77 | HCAR2 (0.80) | — | |
| Diethyl Maleate SCHEMBL2015896 | 0.77 | HCAR2 (0.80) | — | |
| Diethyl Maleate SCHEMBL43033 | 0.77 | HCAR2 (0.80) | — | |
| Diethyl Maleate SCHEMBL60423 | 0.77 | HCAR2 (0.80) | — | |
| Diethyl Maleate SCHEMBL27966383 | 0.77 | HCAR2 (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 746 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456495-A | Sunscreen formulations with reduced tendency to stain fabrics III | 拜尔斯道夫股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| US-9073956-B1 | Dihydro-1H-phosphole 1-oxide derivatives and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2015-07-07 | — | — | US | claimed |
| WO-2014074926-A1 | THERAPEUTIC HYDROXYQUINOLONES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-05-15 | — | — | WO | claimed |
| CN-102850321-A | Aroxylpyrimidine formamide or aroxylpyridine formamide compound and its preparation method, pharmaceutical composition, and application | SHANGHAI INST MATERIA MEDICA | 2013-01-02 | — | — | CN | claimed |
| EP-1454903-B9 | Thiadiazoline derivatives for treating cancer | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-10-05 | — | — | EP | claimed |
| EP-1454903-B1 | Thiadiazoline derivatives for treating cancer | KYOWA HAKKO KIRIN CO LTD (JP) | 2010-09-08 | — | — | EP | claimed |
| US-20090318502-A1 | Pharmaceutical Compositions Comprising a Hypoglycemic Agent and Methods of Using Same | INTRANASAL THERAPEUTICS, INC. (US) | 2009-12-24 | — | — | US | claimed |
| CN-101568258-A | Pyridine derivatives for combating pests | BASF SE (DE) | 2009-10-28 | — | — | CN | claimed |
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | claimed |
| US-20080214660-A1 | Compounds and Methods for the Inhibition of the Expression of VCAM-1 | CRABTREE ACQUISITION CO, LLC | 2008-09-04 | — | — | US | claimed |
| WO-1995026957-A1 | N-HETEROCYCLYL SULPHONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ZENECA LIMITED (GB) | 1995-10-12 | — | — | WO | claimed |
| WO-1995022327-A1 | USE OF 1-(ARYLALKYLAMINOALKYL) IMIDAZOLES FOR TREATING NEUROLOGICAL DAMAGE | KNOLL AG (DE) | 1995-08-24 | — | — | WO | claimed |
| US-5216167-A | Hypoglycemic agents | DR. KARL THOMAE GMBH (DE) | 1993-06-01 | — | — | US | claimed |
| US-5140011-A | Hypotensive agents | HOFFMANN-LA ROCHE, INC. (US) | 1992-08-18 | — | — | US | claimed |
| EP-0144895-B1 | THIOLAN-2,4-DION-3-CARBOXAMIDES | BAYER AG (DE) | 1988-01-20 | — | — | EP | claimed |
| US-4689343-A | AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-25 | — | — | US | claimed |
| US-4628060-A | Fungicidal tetrahydrothiopyran-3,5-dione derivatives, intermediate derivatives, compositions, and method of use therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | claimed |
| US-4599350-A | PHYTOPATHOGENS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-08 | — | — | US | claimed |
| EP-0144895-A2 | Thiolan-2,4-dion-3-carboxamides | BAYER AG (DE) | 1985-06-19 | — | — | EP | claimed |
| EP-0126380-A1 | Substituted tetrahydrothiopyran-3,5-dione-4-carboxamide | BAYER AG (DE) | 1984-11-28 | — | — | EP | claimed |