Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068167 | 1.00 | IKZF2 (0.39) | IKZF2DDB1CRBNCREBBP | |
| SCHEMBL31068124 | 0.87 | CRBN (0.38) | DDB1CRBNCREBBP | |
| SCHEMBL29348692 | 0.86 | DDB1 (0.41) | DDB1CRBNCREBBP | |
| SCHEMBL31068153 | 0.86 | DDB1 (0.41) | DDB1CRBNCREBBP | |
| SCHEMBL29348701 | 0.85 | CRBN (0.35) | DDB1CRBNCREBBP | |
| SCHEMBL31068295 | 0.85 | CRBN (0.35) | DDB1CRBNCREBBP | |
| SCHEMBL31068232 | 0.84 | CRBN (0.40) | DDB1CRBNCREBBP | |
| SCHEMBL29348700 | 0.84 | CRBN (0.40) | DDB1CRBNCREBBP | |
| SCHEMBL31068281 | 0.83 | BMPR1B (0.37) | IKZF2DDB1CRBNCREBBP | |
| SCHEMBL29348605 | 0.80 | DDB1 (0.34) | DDB1CRBNCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |