Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068285 | 1.00 | CRBN (0.39) | CRBNDDB1CNR2HDAC1HDAC8 | |
| SCHEMBL31068258 | 0.89 | DDB1 (0.39) | CRBNDDB1CNR2 | |
| SCHEMBL29348654 | 0.89 | DDB1 (0.39) | CRBNDDB1CNR2 | |
| SCHEMBL29348613 | 0.83 | CRBN (0.41) | CRBNDDB1CNR2HDAC1HDAC8 | |
| SCHEMBL31068162 | 0.83 | CRBN (0.41) | CRBNDDB1CNR2HDAC1HDAC8 | |
| SCHEMBL29348642 | 0.81 | CRBN (0.39) | CRBNDDB1CNR2 | |
| SCHEMBL31068262 | 0.81 | CRBN (0.39) | CRBNDDB1CNR2 | |
| SCHEMBL29348670 | 0.80 | DDB1 (0.42) | CRBNDDB1 | |
| SCHEMBL29348912 | 0.79 | DDB1 (0.38) | CRBNDDB1CNR2 | |
| SCHEMBL31068307 | 0.79 | DDB1 (0.45) | CRBNDDB1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |