Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 5/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068152 | 0.87 | ALOX5AP (0.46) | FEN1ALOX5AP | |
| SCHEMBL31068108 | 0.84 | DDB1 (0.42) | CRBNDDB1 | |
| SCHEMBL29348683 | 0.84 | DDB1 (0.42) | CRBNDDB1 | |
| SCHEMBL31068353 | 0.78 | DDB1 (0.43) | CRBNDDB1 | |
| SCHEMBL31068317 | 0.77 | ALOX5AP (0.43) | FEN1ALOX5APCRBNDDB1 | |
| SCHEMBL29348595 | 0.77 | ALOX5AP (0.43) | FEN1ALOX5APCRBNDDB1 | |
| SCHEMBL31068241 | 0.75 | DDB1 (0.56) | CRBNDDB1 | |
| SCHEMBL31068193 | 0.74 | BRD4 (0.43) | CRBNDDB1 | |
| SCHEMBL29348596 | 0.74 | BRD4 (0.43) | CRBNDDB1 | |
| SCHEMBL31068156 | 0.74 | DDB1 (0.44) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |