Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 13/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068108 | 1.00 | DDB1 (0.42) | DDB1CRBNMAPTKDM4EGSK3B | |
| SCHEMBL31068353 | 0.94 | DDB1 (0.43) | DDB1CRBNCYP1A2CYP2C9CYP11B1 | |
| SCHEMBL31068156 | 0.88 | DDB1 (0.44) | DDB1CRBNMAPTCYP1A2CYP2C9 | |
| SCHEMBL29348689 | 0.88 | DDB1 (0.44) | DDB1CRBNMAPTCYP1A2CYP2C9 | |
| SCHEMBL31068335 | 0.85 | PGR (0.50) | DDB1CRBNCYP1A2CYP11B1CYP11B2 | |
| SCHEMBL31068271 | 0.85 | DDB1 (0.40) | DDB1CRBNPDE3BPDE3A | |
| SCHEMBL29348684 | 0.85 | DDB1 (0.40) | DDB1CRBNPDE3BPDE3A | |
| SCHEMBL29348691 | 0.84 | FEN1 (0.41) | DDB1CRBN | |
| SCHEMBL31068193 | 0.82 | BRD4 (0.43) | DDB1CRBN | |
| SCHEMBL31068286 | 0.82 | CREBBP (0.44) | DDB1CRBNMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |