Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068249 | 1.00 | CYP1A2 (0.32) | CYP1A2CYP2C9CYP2C19GRIN1KCNH2 | |
| SCHEMBL29348893 | 0.75 | NPC1 (0.43) | CYP1A2CYP2C9CYP2C19GRIN1KCNH2 | |
| SCHEMBL31637550 | 0.75 | NPC1 (0.43) | CYP1A2CYP2C9CYP2C19GRIN1KCNH2 | |
| SCHEMBL18069497 | 0.70 | HTT (0.35) | — | |
| SCHEMBL15544326 | 0.70 | HTT (0.35) | — | |
| SCHEMBL30581539 | 0.70 | HTT (0.35) | — | |
| SCHEMBL29348960 | 0.69 | MBOAT4 (0.37) | — | |
| SCHEMBL31637575 | 0.69 | MBOAT4 (0.37) | — | |
| SCHEMBL7704422 | 0.69 | CYP1B1 (0.32) | — | |
| SCHEMBL16213143 | 0.69 | HTT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |