Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 6/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068143 | 1.00 | CRBN (0.35) | CRBNDDB1RBP4FNTAPGGT1B | |
| SCHEMBL29348653 | 0.88 | CRBN (0.36) | CRBNDDB1FNTAPGGT1BIKZF3 | |
| SCHEMBL31068216 | 0.88 | CRBN (0.36) | CRBNDDB1FNTAPGGT1BIKZF3 | |
| SCHEMBL29348551 | 0.84 | CRBN (0.43) | CRBNDDB1IKZF3 | |
| SCHEMBL29348394 | 0.83 | DDB1 (0.43) | CRBNDDB1IKZF3 | |
| SCHEMBL31068194 | 0.83 | CRBN (0.35) | CRBNDDB1IKZF3 | |
| SCHEMBL29348656 | 0.83 | CRBN (0.35) | CRBNDDB1IKZF3 | |
| SCHEMBL29348393 | 0.81 | CNR2 (0.42) | CRBNDDB1IKZF3 | |
| SCHEMBL29348285 | 0.81 | DDB1 (0.41) | CRBNDDB1IKZF3 | |
| SCHEMBL29348667 | 0.79 | CRBN (0.38) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |