SCHEMBL29350133

SCHEMBL29350133

Nc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.80

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.80
P2RY1 P47900 6/20 0.73
ENPP1 P22413 3/20 0.73
P2RX1 P51575 3/20 0.70
P2RX3 P56373 3/20 0.70
P2RX2 Q9UBL9 2/20 0.70
P2RY2 P41231 2/20 0.67
P2RX4 Q99571 2/20 0.67
SRC P12931 1/20 0.67
ALDH1A1 P00352 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
DTYMK P23919 2/20 0.66
RNASEL Q05823 1/20 0.65
MACROD2 A1Z1Q3 1/20 0.63
SIRT6 Q8N6T7 1/20 0.63
MACROD1 Q9BQ69 1/20 0.63
TRPM2 O94759 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5044161 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL3030614 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL29702495 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL14471000 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL18785117 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL78250 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL889289 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL703733 1.00 POLB (0.80) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL31211719 0.99 POLB (0.81) POLBP2RY1ENPP1P2RX1P2RX3
SCHEMBL2508784 0.99 POLB (0.81) POLBP2RY1ENPP1P2RX1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14914 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146272-A1 ENZYMATIC SYNTHESIS OF MODIFIED NUCLEOSIDE TRIPHOSPHATE ANALOGUES ILLUMINA, INC. (US) 2026-05-28 US claimed
CN-122081048-A Portable ultra-fast PCR detection system and application thereof 2026-05-26 CN claimed
CN-122095103-A Mutant DNA polymerase and methods of use thereof 2026-05-26 CN claimed
CN-122070361-A Method for amplifying methylated DNA 辛戴克斯生物有限公司 2026-05-19 CN claimed
CN-122060931-A Kit and method for detecting diarrhea pathogens of various piglets 潍坊华卓生物科技有限公司 2026-05-19 CN claimed
CN-116287331-B Primer, kit and application for lactobacillus reuteri detection 湖南国测生物科技有限公司 2026-05-19 CN claimed
CN-122038615-A Kit for detecting intestinal core bacteria by TaqMan real-time fluorescence quantitative PCR method 大连晶泰医学检验实验室有限公司 2026-05-15 CN claimed
CN-122038548-A QPCR-based DNA methylation rate detection method 苏州海苗生物科技有限公司 2026-05-15 CN claimed
CN-121428075-B High-flux ubiquitin sample protein interaction screening method 良渚实验室 2026-05-15 CN claimed
CN-122038534-A Construction method of DNA library with modified nucleotide and application thereof 深圳华大智造科技股份有限公司 2026-05-15 CN claimed
CN-113862400-B Primer probe combination for detecting new coronavirus and pneumonia pathogenic bacteria and detection kit 上海思路迪医学检验所有限公司 2022-03-08 CN claimed
US-11268075-B2 Inhibition of DNA polymerases by uracil-DNA glycosylase-cleavable oligonucleotide ligands CEPHEID (US) 2022-03-08 US claimed
CN-112175950-B Preparation method of stable circular DNAzyme and its use in Pb2+Applications in assays 农业农村部环境保护科研监测所 2022-03-04 CN claimed
US-20220064699-A1 CONDITIONAL PRIMER EXTENSION FOR SINGLE-MOLECULE DETECTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-03-03 US claimed
CN-114107572-A Primer probe set for detecting different new coronavirus mutant strains based on multiplex PCR technology, detection kit and application of detection kit 潮州凯普生物化学有限公司 2022-03-01 CN claimed
CN-114113267-A Construction method and application of aptamer sensor based on TdT and G4/hemin mimic enzyme amplification technology 郑州大学 2022-03-01 CN claimed
CN-113046452-B Composition for detecting Boeck hollandia farci and application thereof 中国人民解放军陆军军医大学 2022-02-25 CN claimed
CN-114085907-A Method for determining pancreatic cancer progression by MSI2-Numb combined with metabolic molecules 中国医科大学附属第一医院 2022-02-25 CN claimed
CN-114096679-A Nucleic acid amplification method using solid phase carrier 学校法人东京理科大学 2022-02-25 CN claimed
WO-2022040443-A2 A RAPID DIAGNOSTIC TEST FOR LAMP NEW ENGLAND BIOLABS, INC. (US) 2022-02-24 WO claimed