SCHEMBL29350331

SCHEMBL29350331

CC(C)(C)OC(=O)NCc1cc(N)ccc1N

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 1/20 0.45
EPHX2 P34913 1/20 0.41
NR1H4 Q96RI1 1/20 0.41
KCNA5 P22460 1/20 0.41
HDAC1 Q13547 1/20 0.40
AAK1 Q2M2I8 2/20 0.40
IDO1 P14902 3/20 0.39
BRD4 O60885 2/20 0.39
NQO2 P16083 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
HDAC10 Q969S8 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
NAMPT P43490 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12330489 1.00 KDM4A (0.45) KDM4AEPHX2NR1H4KCNA5HDAC1
SCHEMBL23762070 0.88 KCNA5 (0.46) KDM4AEPHX2NR1H4KCNA5HDAC1
SCHEMBL654820 0.88 KDM4A (0.45) KDM4AEPHX2NR1H4KCNA5HDAC1
SCHEMBL13385350 0.88 EPHX2 (0.47) KDM4AEPHX2NR1H4KCNA5HDAC1
SCHEMBL545381 0.86 KDM4A (0.43) KDM4AEPHX2NR1H4KCNA5HDAC1
SCHEMBL5413105 0.86 EPHX2 (0.48) KDM4AEPHX2NR1H4KCNA5IDO1
SCHEMBL2866065 0.86 KDM4A (0.43) KDM4AEPHX2NR1H4KCNA5AAK1
SCHEMBL396084 0.86 KDM4A (0.43) KDM4AEPHX2NR1H4KCNA5HDAC1
SCHEMBL2443309 0.86 GRM2 (0.44) KDM4AKCNA5HDAC1AAK1BRD4
SCHEMBL21987969 0.86 IDO1 (0.48) KDM4AKCNA5IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107338058-B Liquid crystal aligning agent, liquid crystal alignment film and method for producing same, liquid crystal element, polymer and compound JSR株式会社 2022-01-25 CN disclosed