SCHEMBL21987969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21987982	0.89	IDO1 (0.51)	IDO1GAADDR1KDM4AALDH1A1
	SCHEMBL6921464	0.86	IDO1 (0.50)	IDO1GAADDR1KDM4AALDH1A1
	SCHEMBL27988801	0.86	IDO1 (0.53)	IDO1GAADDR1KDM4AALDH1A1
	SCHEMBL29350331	0.86	KDM4A (0.45)	IDO1KDM4AKCNA5
	SCHEMBL12330489	0.86	KDM4A (0.45)	IDO1KDM4AKCNA5
	SCHEMBL711731	0.85	IDO1 (0.50)	IDO1GAAKDM4AALDH1A1HPGD
	SCHEMBL3734185	0.84	ANO1 (0.51)	IDO1GAAKDM4AALDH1A1HPGD
	SCHEMBL2443309	0.83	GRM2 (0.44)	DDR1KDM4AKCNA5
	SCHEMBL4757294	0.83	GAA (0.49)	IDO1GAADDR1KDM4AALDH1A1
	SCHEMBL29793580	0.83	GAA (0.49)	IDO1GAADDR1KDM4AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.