SCHEMBL29351055

SCHEMBL29351055

CC(C)C[C@H](N)C(=O)NC(C)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 9/20 0.51
▸ REN P00797 4/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ F2 P00734 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ LTA4H P09960 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ PEPD P12955 1/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ PTGS1 P23219 1/20 0.51
▸ HTR2A P28223 1/20 0.51
▸ PTGS2 P35354 1/20 0.51
▸ HRH1 P35367 1/20 0.51
▸ THPO P40225 1/20 0.51
▸ PMP22 Q01453 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ ACE2 Q9BYF1 1/20 0.51
▸ DPP4 P27487 1/20 0.48
▸ DPP8 Q6V1X1 1/20 0.48
▸ DPP9 Q86TI2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30008142 1.00 ACE (0.51) ACERENKDM4EF2LMNA
SCHEMBL30399601 0.93 ACE (0.45) ACERENKDM4EF2LMNA
SCHEMBL7757811 0.90 ACE (0.61) ACERENKDM4EF2LMNA
SCHEMBL10733124 0.90 ACE (0.61) ACERENKDM4EF2LMNA
SCHEMBL30661451 0.90 MEN1 (0.47) ACERENKDM4EF2LMNA
SCHEMBL29794187 0.89 ACE (0.50) ACERENKDM4EF2LMNA
SCHEMBL29547044 0.89 ACE (0.53) ACERENKDM4EF2LMNA
SCHEMBL31214680 0.89 ACE (0.52) ACERENKDM4EF2LMNA
SCHEMBL29470154 0.89 ACE (0.52) ACERENKDM4EF2LMNA
SCHEMBL12966251 0.89 ACE (0.52) ACERENKDM4EF2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7449 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310641-A1 Site-specific antibody conjugation and its use HOFFMANN-LA ROCHE INC. (US) 2023-10-05 — — US claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN claimed
US-20220170066-A1 DIFFERENTIATION OF LYME DISEASE AND SOUTHERN TICK-ASSOCIATED RASH ILLNESS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2022-06-02 — — US claimed
US-11230728-B2 Differentiation of lyme disease and southern tick-associated rash illness COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2022-01-25 — — US claimed
CN-108290931-B Novel polypeptides having affinity for PD-L1 AFFIBODY AB (SE) 2026-05-26 — — CN disclosed
CN-114867527-B Macrocyclic peptides Herantis pharmaceutical Co. (FI) 2026-05-26 — — CN disclosed
CN-114729002-B Eluent collection during antibody chromatography MORPHOSYS AG (DE) 2026-05-26 — — CN disclosed
CN-115038722-B Antibodies against KLK5 UCB biopharmaceutical Co.,Ltd. (BE) 2026-05-26 — — CN disclosed
CN-116348115-B Combination of antibody-drug conjugate and PARP1 selective inhibitor ASTRAZENECA UK LTD. (GB) 2026-05-26 — — CN disclosed
CN-116410307-B Neutralizing antibody for neutralizing SARS-CoV-2 in six strains and its application TSINGHUA UNIVERSITY (CN) 2026-05-26 — — CN disclosed
CN-113583116-B Antibodies against SARS-CoV-1 or SARS-CoV-2 and uses thereof 养生堂有限公司 2026-05-22 — — CN disclosed
CN-115135669-B Modified Fc region 硕腾服务有限责任公司 2026-05-19 — — CN disclosed
CN-107206072-B Combination therapy of the T cell activating bispecific antigen binding molecule CD3 ABD folate receptor 1(FolR1) and a PD-1 axis binding antagonist 豪夫迈·罗氏有限公司 2022-01-21 — — CN disclosed
CN-113966344-A anti-BCMA antibody conjugates, compositions comprising the same, and methods of making and using the same 细胞基因公司 2022-01-21 — — CN disclosed
CN-107847592-B Antibodies against human CSF-1R for inducing lymphocytosis in lymphomas or leukemias 豪夫迈·罗氏有限公司 2022-01-21 — — CN disclosed
CN-107001460-B Selective reduction of cysteine residues in IL-17 antibodies 诺华股份有限公司 2022-01-21 — — CN disclosed
CN-113956358-A anti-TIGIT antibodies and methods of use 豪夫迈·罗氏有限公司 2022-01-21 — — CN disclosed
CN-107586340-B Bispecific antibodies specific for T cell activating antigens and tumor antigens and methods of use 罗切格利卡特公司 2022-01-21 — — CN disclosed
CN-113957065-A Sucrose isomerase with high conversion rate and application thereof 南京诺云生物科技有限公司 2022-01-21 — — CN disclosed
CN-113957061-A Administration of kynurenine depleting enzymes for tumor therapy 得克萨斯大学体系董事会 2022-01-21 — — CN disclosed
Send feedback