Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.51 |
| ▸ | REN | P00797 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PEPD | P12955 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351055 | 1.00 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL30399601 | 0.93 | ACE (0.45) | ACERENKDM4EF2LMNA | |
| SCHEMBL7757811 | 0.90 | ACE (0.61) | ACERENKDM4EF2LMNA | |
| SCHEMBL10733124 | 0.90 | ACE (0.61) | ACERENKDM4EF2LMNA | |
| SCHEMBL30661451 | 0.90 | MEN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29794187 | 0.89 | ACE (0.50) | ACERENKDM4EF2LMNA | |
| SCHEMBL29547044 | 0.89 | ACE (0.53) | ACERENKDM4EF2LMNA | |
| SCHEMBL31214680 | 0.89 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL29470154 | 0.89 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL12966251 | 0.89 | ACE (0.52) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108350035-B | Cyclic polypeptides, methods for obtaining them and their use in therapy | 埃克斯欧力提斯药物公司 | 2026-05-19 | — | — | CN | disclosed |
| US-12622975-B2 | Peptide-conjugated prodrugs | BRANDEIS UNIVERSITY (US) | 2026-05-12 | — | — | US | disclosed |
| CN-119899244-A | Enzyme-sensitive PDC type PROTAC modified by human leukemia cell targeting transmembrane peptide, and preparation method and application thereof | 西安交通大学 | 2025-04-29 | — | — | CN | disclosed |
| CN-119792559-A | Cell-penetrating peptide modified enzyme-sensitive PDC PROTAC, and preparation method and application thereof | 西安交通大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-116970080-B | Anti-human MFAP5 monoclonal antibody and preparation method thereof, polynucleotide molecule, expression vector and host cell | 优睿赛思(武汉)生物科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| US-11525155-B2 | Stabilisation of biological samples | QIAGEN GMBH (DE) | 2022-12-13 | — | — | US | disclosed |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | PEPD, PAM, VIP | ACE 1190/4885REN 2773/4885KDM4E 1136/4885 |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | VIP, DNPEP, PEPD | ACE 486/4885REN 3056/4885KDM4E 4697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.