SCHEMBL29351086

SCHEMBL29351086

O=c1ccc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 1.00
CA9 Q16790 5/20 1.00
CA1 P00915 2/20 1.00
CA4 P22748 2/20 1.00
CA6 P23280 2/20 1.00
CA3 P07451 1/20 1.00
CA5A P35218 1/20 1.00
CA7 P43166 1/20 1.00
CA13 Q8N1Q1 1/20 1.00
CA14 Q9ULX7 1/20 1.00
CA5B Q9Y2D0 1/20 1.00
ALDH1A1 P00352 1/20 0.54
PDE3B Q13370 2/20 0.52
PDE3A Q14432 2/20 0.52
F11 P03951 1/20 0.52
BRD4 O60885 1/20 0.47
DAO P14920 1/20 0.47
DDO Q99489 1/20 0.47
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5437282 1.00 CA12 (1.00) CA12CA9CA1CA4CA6
SCHEMBL30958273 1.00 CA12 (1.00) CA12CA9CA1CA4CA6
SCHEMBL8621 1.00 CA12 (1.00) CA12CA9CA1CA4CA6
SCHEMBL14353322 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
SCHEMBL29227206 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
SCHEMBL29489169 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
Hydrochloric Acid SCHEMBL4429445 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
Water SCHEMBL10661261 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
SCHEMBL6283613 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
Hydrochloric Acid SCHEMBL1824447 0.98 CA12 (0.95) CA12CA9CA1CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3279 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747245-A1 PHARMACEUTICAL COMPOUNDS Almac Discovery Limited (GB) 2026-05-27 EP claimed
CN-122079886-A Axis chiral 1,4' -biquinolinone and derivative and synthetic method thereof 2026-05-26 CN claimed
CN-122079888-A Marbofloxacin intermediate 2026-05-26 CN claimed
CN-122010968-A Furanoquinoline dictamnine derivative and preparation method and application thereof 广东药科大学 2026-05-12 CN claimed
US-12600738-B2 Quinolinone derivative compound selectively binding to cysteine, peptide conjugate thereof, and antibody-drug conjugate comprising same INSTITUTE FOR BASIC SCIENCE; (KR) 2026-04-14 US claimed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US claimed
US-20260090198-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, LIGHT-EMITTING MODULE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2026-03-26 US claimed
EP-4702981-A1 TARGETED ANTIBACTERIAL TREATMENT Københavns Universitet (DK) 2026-03-04 EP claimed
EP-4696305-A1 LIPID NANOPARTICLES TARGETING SPLEEN Beijing Jitai Pharmaceutical Technology Co., Ltd. (CN) 2026-02-18 EP claimed
EP-4695230-A1 PROTEASE INHIBITORS AND USES THEREOF Westlake Pharmaceuticals (Hangzhou) Co., Ltd. (CN) 2026-02-18 EP claimed
CN-114196623-A Application of quinolinone compound as osteogenic differentiation promoter of stem cells between bone marrows 青岛大学附属医院 2022-03-18 CN claimed
CN-114163446-A Quinoline ketone skeleton PDE4 inhibitor and preparation method and application thereof 中山大学 2022-03-11 CN claimed
CN-114166960-A Detection method of brexpiprazole related substance 西安远大科创医药科技有限公司 2022-03-11 CN claimed
WO-2022045773-A1 QUINOLINONE DERIVATIVE COMPOUND SELECTIVELY BINDING TO CYSTEINE, PEPTIDE CONJUGATE THEREOF, AND ANTIBODY-DRUG CONJUGATE COMPRISING SAME 기초과학연구원 2022-03-03 WO claimed
CN-112390750-B Quinolinone compounds as selective phosphodiesterase 2 inhibitors and preparation method thereof 常州大学 2022-03-01 CN claimed
WO-2022034916-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2022-02-17 WO claimed
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-15 US claimed
US-11242363-B2 Compositions and methods for stereoregular ring expansion metathesis polymerization UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2022-02-08 US claimed
WO-2022017444-A1 SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF 贝达药业股份有限公司 2022-01-27 WO claimed
US-11230556-B2 6,5-fused heteroaryl piperidine ether allosteric modulators of the M4 muscarinic acetylcholine receptor MERCK SHARP & DOHME CORP. (US) 2022-01-25 US claimed