SCHEMBL8621

SCHEMBL8621

O=c1ccc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 1.00
CA9 Q16790 5/20 1.00
CA1 P00915 2/20 1.00
CA4 P22748 2/20 1.00
CA6 P23280 2/20 1.00
CA3 P07451 1/20 1.00
CA5A P35218 1/20 1.00
CA7 P43166 1/20 1.00
CA13 Q8N1Q1 1/20 1.00
CA14 Q9ULX7 1/20 1.00
CA5B Q9Y2D0 1/20 1.00
ALDH1A1 P00352 1/20 0.54
PDE3B Q13370 2/20 0.52
PDE3A Q14432 2/20 0.52
F11 P03951 1/20 0.52
BRD4 O60885 1/20 0.47
DAO P14920 1/20 0.47
DDO Q99489 1/20 0.47
GRIN2D O15399 2/20 0.46
GRIN3B O60391 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5437282 1.00 CA12 (1.00) CA12CA9CA1CA4CA6
SCHEMBL29351086 1.00 CA12 (1.00) CA12CA9CA1CA4CA6
SCHEMBL30958273 1.00 CA12 (1.00) CA12CA9CA1CA4CA6
SCHEMBL14353322 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
SCHEMBL29227206 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
SCHEMBL29489169 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
Hydrochloric Acid SCHEMBL4429445 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
Water SCHEMBL10661261 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
SCHEMBL6283613 0.98 CA12 (0.95) CA12CA9CA1CA4CA6
Hydrochloric Acid SCHEMBL1824447 0.98 CA12 (0.95) CA12CA9CA1CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 66688 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637410-B2 Vesicular monoamine transporter-2 ligands and their use in the treatment of psychostimulant abuse UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2026-05-26 US claimed
US-20260124198-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-07 US claimed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP claimed
EP-4678634-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Haihe Biopharma Co., Ltd. (CN) 2026-01-14 EP claimed
EP-4674482-A2 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS ASSOCIATED WITH NEURODEGENERATIVE DISEASE OR IMPULSIVE SYMPTOMS ASSOCIATED WITH MENTAL DISEASE CONTAINING BREXPIPRAZOLE OR SALT THEREOF Otsuka Pharmaceutical Co., Ltd. (JP) 2026-01-07 EP claimed
US-20250353828-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-20 US claimed
US-20250332117-A1 Thin Films with Peroxides and Uses Thereof Silverpeutics, Inc. (US) 2025-10-30 US claimed
US-20250313535-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF DICE MOLECULES SV, INC. 2025-10-09 US claimed
US-20250248988-A1 COMBINATION USES OF NITROXOLINE AND ITS ANALOGUES WITH CHEMOTHERAPIES AND IMMUNOTHERAPIES IN THE TREATMENT OF CANCERS JIANGSU YAHONG MEDITECH CO., LTD. (CN) 2025-08-07 US claimed
WO-2025122555-A1 S1P 1 RECEPTOR AGONISTS AND USES THEREOF VALO HEALTH, INC. (US) 2025-06-12 WO claimed
US-4223137-A DILATION, HYPOTENSIVES, ANTIHISTAMINES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1980-09-16 US claimed
EP-0014012-A1 Photosensitive composition containing an ethylenically unsaturated compound, initiator and sensitizer AGFA-GEVAERT N.V. (BE) 1980-08-06 EP claimed
US-4210753-A TREATMENT OF CARDIAC DISORDERS AND CHRONIC LUNG DISEASE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1980-07-01 US claimed
EP-0006506-A1 Carbostyrile derivatives, processes for their preparation and pharmaceutical compositions containing them Roche Diagnostics GmbH (DE) 1980-01-09 EP claimed
EP-0003771-A1 Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them Dr. Karl Thomae GmbH (DE) 1979-09-05 EP claimed
US-4071520-A Method for preparing carbostyril derivatives IMC CHEMICAL GROUP, INC. (US) 1978-01-31 US claimed
US-4022784-A PHARMACEUTICALS OTSUKA PHARMACEUTICAL COMPANY LIMITED (JA) 1977-05-10 US claimed
US-4002734-A CONTROLLING LOOSE DANDRUFF, LUBRICATING HAIR TO IMPROVE TEXTURE AND MANAGEABILITY PICKFORD MELCINA H 1977-01-11 US claimed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US claimed
US-3947412-A CYCLIZATION IN THE PRESENCE OF HEAVY METALS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US claimed