Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 12/20 | 0.73 |
| ▸ | KDM4A | O75164 | 12/20 | 0.73 |
| ▸ | HIF1AN | Q9NWT6 | 12/20 | 0.73 |
| ▸ | KDM2A | Q9Y2K7 | 12/20 | 0.73 |
| ▸ | KDM4D | Q6B0I6 | 11/20 | 0.73 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | TTK | P33981 | 1/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 10/20 | 0.46 |
| ▸ | KDM3B | Q7LBC6 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766387 | 0.84 | KDM6B (1.00) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL9956612 | 0.84 | KDM6B (0.75) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL29812327 | 0.77 | BAZ2B (0.44) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL13525026 | 0.74 | KDM6B (0.61) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL19725083 | 0.74 | KDM6B (0.56) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL11627502 | 0.72 | KDM6B (0.40) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL10783573 | 0.72 | KDM6B (0.57) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL3577936 | 0.72 | KDM6B (0.58) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL2072718 | 0.71 | KDM6B (0.56) | KDM6BKDM4AHIF1ANKDM2AKDM4D | |
| SCHEMBL2713726 | 0.71 | KDM6B (0.56) | KDM6BKDM4AHIF1ANKDM2AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476642-B | Compounds and their use for reducing uric acid levels | 阿奎斯特有限责任公司 | 2022-01-25 | — | — | CN | disclosed |