Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Exatecan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 known ✓ | P11387 | 19/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Exatecan SCHEMBL7255477 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL31615015 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL29601765 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL23471938 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL2512959 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL25349032 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL7249645 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL26320 | 1.00 | TOP1 (0.60) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL7163616 | 0.99 | TOP1 (0.59) | TOP1MEN1KMT2A | |
| Exatecan SCHEMBL6047672 | 0.99 | TOP1 (0.59) | TOP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 458 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116304486-B | Convex polygon parameter calculation method for pose monitoring and metal wire weaving monitoring | 西安科技大学 | 2026-02-27 | — | — | CN | claimed |
| US-12493141-B2 | Camera module, imaging module and electronic device | LARGAN PRECISION CO., LTD. (TW) | 2025-12-09 | — | — | US | claimed |
| CN-120200741-A | Key recovery method and storage medium of SM2 signature algorithm based on lattice attack | 上海华虹集成电路有限责任公司 | 2025-06-24 | — | — | CN | claimed |
| CN-120143734-A | Five-axis numerical control machining non-interference smooth tool path generation method for blade root area | 苏州科技大学 | 2025-06-13 | — | — | CN | claimed |
| WO-2025118880-A1 | VOLTAGE RATIO OVER-RANGE SELF-CALIBRATION METHOD, COMPUTER DEVICE, AND STORAGE MEDIUM | 长沙天恒测控技术有限公司 | 2025-06-12 | — | — | WO | claimed |
| US-20250165220-A1 | METHOD FOR THE COMPUTATION OF A NARROW BIT WIDTH LINEAR ALGEBRA OPERATION | BARCELONA SUPERCOMPUTING CENTER - CENTRO NACIONAL DE SUPERCOMPUTACIÓN (BSC-CNS) (ES) | 2025-05-22 | — | — | US | claimed |
| CN-119958652-A | Urban river flow measuring device and measuring method | 上海勘测设计研究院有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-115420186-B | Method and device for detecting pulse vortex of diameter of steel bar based on parameter inversion | 北京航空航天大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119743055-A | Model prediction control method based on discrete space vector modulation | 华中科技大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119199720-B | DOA estimation method and device without source number priori | 中国科学院声学研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-111951125-B | Transformer area abnormal user variation relation identification method based on big data analysis | 积成电子股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-216313212-U | Ultra-micro-distance AF camera module and mobile terminal | 重庆市天实精工科技有限公司 | 2022-04-15 | — | — | CN | claimed |
| US-20220112119-A1 | GLASS-BASED ARTICLES AND PROPERTIES THEREOF | CORNING INCORPORATED (US) | 2022-04-14 | — | — | US | claimed |
| CN-112692707-B | Six-linkage polishing method | 枣庄北航机床创新研究院有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-113299317-B | Intersection collision audio early warning evaluation method based on MFCC feature extraction | 东南大学 | 2022-04-08 | — | — | CN | claimed |
| CN-114241067-A | Capacitance tomography image reconstruction method based on polynomial regeneration sampling kernel | 浙江工业大学 | 2022-03-25 | — | — | CN | claimed |
| US-20220085823-A1 | Linearization of Digital-to-Analog Converters (DACs) and Analog-to-Digital Converters (ADCs) and Associated Methods | MIXED-SIGNAL DEVICES INC. (US) | 2022-03-17 | — | — | US | claimed |
| CN-114189268-A | Signal spectrum, carrier frequency and DOA joint estimation method based on beam forming MWC | 哈尔滨工业大学 | 2022-03-15 | — | — | CN | claimed |
| CN-110206536-B | Wellhead liquid production amount acquisition method based on pump indicator diagram | 海默潘多拉数据科技(深圳)有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114089768-A | LMB-based two-stage SLAM feature point detection and marking method | 陕西科技大学 | 2022-02-25 | — | — | CN | claimed |