Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | PRCP | P42785 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30555944 | 1.00 | DRD2 (0.61) | DRD2DRD1PRCPESR1ESR2 | |
| SCHEMBL2935206 | 1.00 | DRD2 (0.61) | DRD2DRD1PRCPESR1ESR2 | |
| SCHEMBL11445243 | 1.00 | DRD2 (0.61) | DRD2DRD1PRCPESR1ESR2 | |
| SCHEMBL12090226 | 0.84 | SLC6A4 (0.54) | DRD2DRD1PRCPOPRM1OPRK1 | |
| SCHEMBL14032145 | 0.84 | ESR1 (0.70) | DRD2DRD1PRCPESR1ESR2 | |
| SCHEMBL7662243 | 0.83 | DRD1 (0.60) | DRD2DRD1DRD4KDM4EALDH1A1 | |
| SCHEMBL13356369 | 0.82 | DRD2 (0.67) | DRD2DRD1ESR1ESR2DRD4 | |
| SCHEMBL14848646 | 0.82 | DRD2 (0.76) | DRD2DRD1DRD4KDM4EALDH1A1 | |
| SCHEMBL23057928 | 0.81 | PRCP (0.56) | DRD2DRD1PRCPOPRM1OPRK1 | |
| SCHEMBL21890121 | 0.81 | PRCP (0.56) | DRD2DRD1PRCPOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |