Fanapanel

Fanapanel

SCHEMBL29352240

O=c1[nH]c2cc(C(F)(F)F)c(N3CCOCC3)cc2n(CP(=O)(O)O)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 11/20 0.51
GRIA2 P42262 11/20 0.51
GRIA3 P42263 11/20 0.51
GRIA4 P48058 11/20 0.51
GRIN2D O15399 1/20 0.51
GRIN3B O60391 1/20 0.51
GRIN1 Q05586 1/20 0.51
GRIN2A Q12879 1/20 0.51
GRIN2B Q13224 1/20 0.51
GRIN2C Q14957 1/20 0.51
GRIN3A Q8TCU5 1/20 0.51
GRIK1 P39086 5/20 0.48
GRIK2 Q13002 5/20 0.48
GRIK3 Q13003 5/20 0.48
GRIK4 Q16099 5/20 0.48
GRIK5 Q16478 5/20 0.48
NOTUM Q6P988 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fanapanel SCHEMBL353357 1.00 GRIA1 (0.51) GRIA1GRIA2GRIA3GRIA4GRIN2D
Fanapanel SCHEMBL30546194 0.99 GRIA1 (0.50) GRIA1GRIA2GRIA3GRIA4GRIN2D
Fanapanel SCHEMBL25432377 0.99 GRIA1 (0.50) GRIA1GRIA2GRIA3GRIA4GRIN2D
SCHEMBL8107335 0.90 GRIA1 (0.53) GRIA1GRIA2GRIA3GRIA4GRIN2D
SCHEMBL8122798 0.90 GRIA1 (0.53) GRIA1GRIA2GRIA3GRIA4GRIN2D
SCHEMBL8340446 0.87 GRIA1 (0.50) GRIA1GRIA2GRIA3GRIA4GRIN2D
SCHEMBL7088166 0.86 GRIA1 (0.47) GRIA1GRIA2GRIA3GRIA4GRIN2D
SCHEMBL2037840 0.86 GRIA1 (0.49) GRIA1GRIA2GRIA3GRIA4GRIN2D
SCHEMBL8341491 0.85 GRIA1 (0.43) GRIA1GRIA2GRIA3GRIA4GRIN2D
SCHEMBL7885810 0.84 GRIA1 (0.48) GRIA1GRIA2GRIA3GRIA4GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4475953-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN, Fikret (TR) 2024-12-18 EP claimed
CN-119095622-A NMDAR antagonists prevent aging and aging-related conditions and diseases by increasing 20S proteasome activity 菲克雷特·萨欣 2024-12-06 CN claimed
WO-2023154014-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN FIKRET (TR) 2023-08-17 WO claimed
US-12616807-B2 Medical counter measures including dry powder formulations and associated methods Belhaven BioPharma Inc. (US) 2026-05-05 US disclosed
US-20250288544-A1 PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) 2025-09-18 US disclosed
US-20250281474-A1 PHARMACEUTICAL COMPOSITION FOR TREATING COGNITIVE DECLINE OR FOR TREATING OVERWEIGHTNESS OR OBESITY UNIVERSITY OF THE RYUKYUS (JP) 2025-09-11 US disclosed
US-12370233-B2 Depot systems comprising glatiramer acetate MAPI PHARMA LTD. (IL) 2025-07-29 US disclosed
CN-114614625-B Efficient and energy-saving heat dissipation device for variable frequency motor 马勇 2025-06-24 CN disclosed
US-12318358-B2 Probenecid for use in treating epileptic diseases, disorders or conditions PARIS SCIENCES ET LETTRES (FR) 2025-06-03 US disclosed
US-20250161238-A1 NMDAR Antagonists Prevent Ageing and Aging-Associated Conditions and Diseases Through Increasing 20S Proteasome Activity SAHIN FIKRET (TR) 2025-05-22 US disclosed
US-12297997-B1 Fan lamp Yu Huanyuan (CN) 2025-05-13 US disclosed
CN-113955230-B Intelligent processing method and production line of camel fresh milk 阿拉善左旗梦可草原牧业食品专业合作社 2023-03-17 CN disclosed
WO-2023010713-A1 TEMPERATURE-COMPENSATION-TYPE AIR-COOLED OIL COOLER 浙江尔格科技股份有限公司 2023-02-09 WO disclosed
US-11490856-B2 Method and a system for analyzing neuropharmacology of a drug CITY UNIVERSITY OF HONG KONG (HK) 2022-11-08 US disclosed
CN-216812298-U Fan installation jig 浙江日风电气股份有限公司 2022-06-24 CN disclosed
CN-114614625-A Efficient and energy-saving heat dissipation device for variable frequency motor 马勇 2022-06-10 CN disclosed
CN-114263080-A High-pressure flushing and dredging device for sewage pipeline 苏州净沐环保科技有限公司 2022-04-01 CN disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
CN-215809467-U Ultralow-temperature drug storage evaporator 济南康斐净化技术有限公司 2022-02-11 CN disclosed
CN-113955230-A Intelligent processing method and production line of camel fresh milk 阿拉善左旗梦可草原牧业食品专业合作社 2022-01-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288544-A1 PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS NLN, CLN6, SLC1A2 GRIA1 346/4885GRIA2 127/4885GRIA3 170/4885
US-12616807-B2 Medical counter measures including dry powder formulations and associated methods ADRB2, ADRB3, MC5R GRIA1 1312/4885GRIA2 1365/4885GRIA3 1422/4885
US-12318358-B2 Probenecid for use in treating epileptic diseases, disorders or conditions NLN, CLN6, SLC1A2 GRIA1 346/4885GRIA2 127/4885GRIA3 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.