SCHEMBL29352292

SCHEMBL29352292

Cc1cc(-c2ccccc2C)n(-c2ccc(S(N)(=O)=O)cc2)n1

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 9/20 0.74
PTGS1 P23219 5/20 0.74
PTGES O14684 1/20 0.56
ALOX5 P09917 1/20 0.55
MMP2 P08253 2/20 0.55
CA1 P00915 4/20 0.53
CA2 P00918 4/20 0.53
CA9 Q16790 3/20 0.53
CA12 O43570 1/20 0.52
CA5A P35218 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
CYP2C9 P11712 1/20 0.52
PDPK1 O15530 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3239998 0.85 PTGS2 (1.00) PTGS2PTGS1PTGESALOX5CA1
SCHEMBL5226958 0.84 PTGS2 (1.00) PTGS2PTGS1PTGESALOX5MMP2
SCHEMBL16026063 0.82 PTGS2 (0.59) PTGS2PTGS1PTGESALOX5CA1
SCHEMBL6013916 0.82 PTGS2 (0.67) PTGS2PTGS1PTGESMMP2
SCHEMBL16301172 0.81 NPC1 (0.67) PTGS2PTGS1ALOX5CYP2C9
SCHEMBL8121094 0.81 PTGS2 (0.69) PTGS2PTGS1MMP2CYP2C9PDPK1
SCHEMBL6013912 0.81 PTGS2 (0.72) PTGS2PTGS1PTGESCA1CA2
SCHEMBL6013910 0.81 PTGS2 (0.80) PTGS2PTGS1PTGESALOX5CA1
SCHEMBL14280457 0.81 PTGS2 (0.90) PTGS2PTGS1PTGESALOX5CA1
SCHEMBL3103964 0.80 PTGS2 (0.78) PTGS2PTGS1PTGESALOX5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11902616-B2 Audio-visual device D&M HOLDINGS, INC. (JP) 2024-02-13 US disclosed
EP-3522551-B1 AUDIO/VIDEO DEVICE D & M HOLDINGS INC (JP) 2023-05-10 EP disclosed
US-20220121539-A1 AUDIO-VISUAL DEVICE D&M HOLDINGS, INC. (JP) 2022-04-21 US disclosed
US-11234045-B2 Audio-visual device D&M HOLDINGS, INC. (JP) 2022-01-25 US disclosed