SCHEMBL2935272

SCHEMBL2935272

N#Cc1cncc(C=Cc2ccccc2)c1Nc1ccc2cc[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRKCQ Q04759 20/20 1.00
PRKCD Q05655 15/20 0.86
PRKCB P05771 1/20 0.47
LCK P06239 1/20 0.47
LYN P07948 1/20 0.47
PRKCH P24723 1/20 0.47
PRKCE Q02156 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2936308 1.00 PRKCQ (1.00) PRKCQPRKCDPRKCBLCKLYN
SCHEMBL2935239 0.93 PRKCQ (1.00) PRKCQPRKCDLYNPRKCHPRKCE
SCHEMBL31061266 0.93 PRKCQ (1.00) PRKCQPRKCDLYNPRKCHPRKCE
SCHEMBL2934504 0.83 PRKCQ (1.00) PRKCQPRKCD
SCHEMBL2934507 0.83 PRKCQ (1.00) PRKCQPRKCD
SCHEMBL2933197 0.82 PRKCQ (0.69) PRKCQPRKCDLYNPRKCHPRKCE
SCHEMBL2933194 0.82 PRKCQ (0.69) PRKCQPRKCDLYNPRKCHPRKCE
SCHEMBL2929104 0.80 PRKCQ (0.76) PRKCQPRKCDPRKCBLCKLYN
SCHEMBL2936220 0.80 PRKCQ (1.00) PRKCQPRKCD
SCHEMBL2934672 0.78 PRKCQ (0.76) PRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2229377-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS Wyeth LLC (US) 2010-09-22 EP claimed
WO-2009076602-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS WYETH (US) 2009-06-18 WO claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
EP-2229377-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS Wyeth LLC (US) 2010-09-22 EP disclosed
WO-2009076602-A1 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS WYETH (US) 2009-06-18 WO disclosed