⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286070 | 1.00 | — | — | |
| SCHEMBL27781023 | 1.00 | G6PC1 (0.34) | — | |
| SCHEMBL27309552 | 1.00 | G6PC1 (0.34) | — | |
| SCHEMBL27781040 | 1.00 | G6PC1 (0.34) | — | |
| SCHEMBL9803968 | 1.00 | G6PC1 (0.34) | — | |
| SCHEMBL9803967 | 1.00 | G6PC1 (0.34) | — | |
| SCHEMBL27781018 | 1.00 | G6PC1 (0.34) | — | |
| SCHEMBL286069 | 1.00 | — | — | |
| SCHEMBL294151 | 0.97 | — | — | |
| SCHEMBL285767 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200113-B2 | Multi-amine functional oligomers and method for producing the same by the reduction of corresponding oximes | COVESTRO DEUTSCHLAND AG (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2427457-B1 | ISOXAZOLE-PYRIDINE DERIVATIVES AS GABA MODULATORS | HOFFMANN LA ROCHE (CH) | 2013-07-17 | — | — | EP | disclosed |
| US-8357703-B2 | Pyridines | HOFFMANN-LA ROCHE INC. (US) | 2013-01-22 | — | — | US | disclosed |
| EP-2043441-B1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-09-12 | — | — | EP | disclosed |
| EP-2427457-A1 | ISOXAZOLE-PYRIDINE DERIVATIVES AS GABA MODULATORS | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| WO-2010127978-A1 | ISOXAZOLE-PYRIDINE DERIVATIVES AS GABA MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286117-A1 | PYRIDINES | ROCHE PALO ALTO LLC | 2010-11-11 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| EP-0373549-B1 | AMINO ACID DERIVATIVES WITH ENZYME-INHIBITING PROPERTIES, PROCESS TO SYNTHETISE THEM, COMPOSITION CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-01 | — | — | EP | disclosed |
| US-5185324-A | ENZYME-INHIBITING AMINO ACID DERIVATIVES, A PROCESS FOR THE PREPARATION THEREOF, AGENTS CONTAINING THESE, AND THE USE THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |
| EP-0373549-A2 | Amino acid derivatives with enzyme-inhibiting properties, process to synthetise them, composition containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| US-4812587-A | Process for selective hydrogenation of C--C double bonds in the presence of reducible, nitrogen-containing groups and new ruthenium complex compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-14 | — | — | US | disclosed |
| EP-0138141-B1 | PROCESS FOR THE SELECTIVE HYDROGENATION OF C-C DOUBLE BONDS IN THE PRESENCE OF REDUCIBLE NITROGEN-CONTAINING GROUPS | BAYER AG (DE) | 1988-02-24 | — | — | EP | disclosed |
| US-4673757-A | Process for selective hydrogenation of C-C double bonds in the presence of reducible, nitrogen-containing groups and new ruthenium complex compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-16 | — | — | US | disclosed |
| EP-0080700-B1 | A PROCESS FOR PRODUCING NITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0138141-A1 | Process for the selective hydrogenation of C-C double bonds in the presence of reducible nitrogen-containing groups | BAYER AG (DE) | 1985-04-24 | — | — | EP | disclosed |
| US-4456562-A | AZEOTROPIC DISTILLATION OF WATER FROM REACTION PRODUCT OF ANALDEHYDE AND HYDROXYLAMINE OR ALDOXIME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-06-26 | — | — | US | disclosed |
| EP-0080700-A1 | A process for producing nitrile compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-08 | — | — | EP | disclosed |