SCHEMBL29353099

SCHEMBL29353099

COc1ccc2c(c1)c(C1=C(c3c[nH]c4ccccc34)C(=O)NC1=O)cn2CCCN(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKD1 Q15139 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
PRKACA P17612 10/20 0.78
PRKACG P22612 10/20 0.78
PRKACB P22694 10/20 0.78
GSK3B P49841 5/20 0.78
CDK4 P11802 3/20 0.78
CCND1 P24385 3/20 0.78
PRKCA P17252 3/20 0.78
CCNB2 O95067 3/20 0.78
CDK1 P06493 3/20 0.78
CCNB1 P14635 3/20 0.78
CCNB3 Q8WWL7 3/20 0.78
PIM1 P11309 2/20 0.78
PRKCB P05771 2/20 0.78
PRKCH P24723 2/20 0.78
PRKCQ Q04759 2/20 0.78
PRKCD Q05655 2/20 0.78
MEN1 O00255 1/20 0.78
PRKD3 O94806 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29525501 1.00 PRKD1 (1.00) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL1680253 1.00 PRKD1 (1.00) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL29041083 0.96 PRKD1 (0.92) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL9085119 0.95 PRKD1 (0.90) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL7814801 0.94 PRKD1 (0.88) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL7823817 0.93 PRKD1 (0.87) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL9086159 0.93 PRKD1 (0.87) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL7815373 0.91 PRKD1 (0.84) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL9085659 0.89 PRKD1 (0.81) PRKD1TDP1PRKACAPRKACGPRKACB
SCHEMBL9083990 0.89 PRKD1 (0.81) PRKD1TDP1PRKACAPRKACGPRKACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382583-A1 ENHANCED METHODS FOR INDUCING AND MAINTAINING NAIVE HUMAN PLURIPOTENT STEM CELLS WASHINGTON UNIVERSITY ST LOUIS (US) 2025-12-18 US claimed
EP-4599048-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS Trailhead Biosystems Inc. (US) 2025-08-13 EP claimed
US-12385009-B2 Methods and compositions for generating oligodendrocyte progenitor cells TRAILHEAD BIOSYSTEMS INC. (US) 2025-08-12 US claimed
US-12385008-B2 Method for producing retinal tissue Sumitomo Pharma Co., Ltd. (JP) 2025-08-12 US claimed
US-12371667-B2 Enhanced methods for inducing and maintaining naive human pluripotent stem cells WASHINGTON UNIVERSITY (US) 2025-07-29 US claimed
US-20250163388-A1 METHODS FOR DERIVATION AND PROPAGATION OF AVIAN PLURIPOTENT STEM CELLS AND APPLICATIONS THEREOF UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-05-22 US claimed
CN-119842617-A Method for preparing retinal pigment epithelial cells 住友制药株式会社 2025-04-18 CN claimed
CN-119432723-A Goat embryonic stem cell culture system, construction method and application 西北农林科技大学 2025-02-14 CN claimed
US-12221625-B2 Method for producing retinal pigment epithelial cells Sumitomo Pharma Co., Ltd. (JP) 2025-02-11 US claimed
CN-119193488-A Method for reprogramming rat skin fibroblasts into neuronal cells 蚌埠医科大学 2024-12-27 CN claimed
US-20230031009-A1 TREATMENT FOR CHEMOBRAIN UNIV YALE (US) 2023-02-02 US claimed
WO-2022211893-A9 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2022-12-08 WO claimed
EP-4092109-A1 METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIAL CELLS Sumitomo Pharma Co., Ltd. (JP) 2022-11-23 EP claimed
CN-108060120-B Small molecule compound combination for differentiated cell reprogramming, kit and application 云南济慈再生医学研究院有限公司 2022-11-04 CN claimed
US-20220315891-A1 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. 2022-10-06 US claimed
WO-2022211893-A1 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2022-10-06 WO claimed
CN-114891726-A Human totipotent-like stem cell induction culture medium and application thereof 中山大学 2022-08-12 CN claimed
WO-2022124342-A1 AGENT FOR CANCER THERAPY, AND SCREENING METHOD FOR ACTIVE INGREDIENT THEREOF 国立大学法人 岡山大学 2022-06-16 WO claimed
EP-3354721-B1 METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIAL CELLS SUMITOMO PHARMA CO LTD (JP) 2022-06-08 EP claimed
CN-113265375-B Method for improving cell activity 云南济慈再生医学研究院有限公司 2022-05-13 CN claimed