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Sugi Predict / Compounds / SCHEMBL29353374

SCHEMBL29353374

SCHEMBL29353374

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CTSD P07339 1/20 0.47
▸ BACE1 P56817 1/20 0.47
▸ GLP1R P43220 6/20 0.47
▸ GIPR P48546 6/20 0.47
▸ RAMP1 O60894 1/20 0.46
▸ CALCRL Q16602 1/20 0.46
▸ NPY2R P49146 6/20 0.46
▸ NPY4R P50391 6/20 0.46
▸ NPY5R Q15761 6/20 0.46
▸ NPY1R P25929 4/20 0.46
▸ RAMP3 O60896 4/20 0.45
▸ CALCR P30988 4/20 0.45
▸ EP300 Q09472 1/20 0.45
▸ HIF1A Q16665 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29518457 0.95 BACE1 (0.47) CTSDBACE1GLP1RGIPRRAMP1
Human C-Peptide SCHEMBL29353643 0.95 NPY2R (0.50) GLP1RGIPRNPY2RNPY4RNPY5R
SCHEMBL29353296 0.94 NPY2R (0.47) GLP1RGIPRNPY2RNPY4RNPY5R
SCHEMBL30526237 0.87 NPY2R (0.60) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL29855903 0.87 NPY2R (0.53) GLP1RGIPRNPY2RNPY4RNPY5R
SCHEMBL29424684 0.86 RAMP3 (0.56) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30906558 0.85 RAMP3 (0.47) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30906409 0.85 RAMP3 (0.47) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL30262183 0.85 NPY2R (0.54) CTSDBACE1NPY2RNPY4RNPY5R
SCHEMBL29479863 0.85 NPY2R (0.52) GLP1RGIPRNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117487026-A insulin-Fc fusion protein and application thereof 江苏晟斯生物制药有限公司 2024-02-02 — — CN disclosed
CN-113968911-B insulin-Fc fusion protein and application thereof 江苏晟斯生物制药有限公司 2023-10-10 — — CN disclosed
EP-4230216-A1 INSULIN-FC FUSION PROTEIN AND APPLICATION THEREOF Jiangsu Gensciences Inc. (CN) 2023-08-23 — — EP disclosed
WO-2022017309-A1 INSULIN-FC FUSION PROTEIN AND APPLICATION THEREOF 江苏晟斯生物制药有限公司 2022-01-27 — — WO disclosed
CN-113968911-A insulin-Fc fusion protein and application thereof 江苏晟斯生物制药有限公司 2022-01-25 — — CN disclosed
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