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SCHEMBL29518457

SCHEMBL29518457

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)CNC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 2/20 0.47
▸ CTSD P07339 1/20 0.47
▸ CALCRL Q16602 2/20 0.45
▸ RAMP1 O60894 1/20 0.45
▸ GLP1R P43220 6/20 0.45
▸ GIPR P48546 6/20 0.45
▸ RAMP3 O60896 5/20 0.43
▸ CALCR P30988 5/20 0.43
▸ NPY2R P49146 3/20 0.43
▸ NPY4R P50391 3/20 0.43
▸ NPY5R Q15761 3/20 0.43
▸ NPY1R P25929 2/20 0.43
▸ NAA50 Q9GZZ1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353374 0.95 CTSD (0.47) BACE1CTSDCALCRLRAMP1GLP1R
Human C-Peptide SCHEMBL29353643 0.93 NPY2R (0.50) GLP1RGIPRRAMP3CALCRNPY2R
SCHEMBL29353296 0.90 NPY2R (0.47) GLP1RGIPRRAMP3CALCRNPY2R
SCHEMBL29424684 0.88 RAMP3 (0.56) RAMP3CALCRNPY2RNPY4RNPY5R
SCHEMBL30608602 0.85 NAA50 (0.48) CALCRLNAA50
SCHEMBL30608590 0.85 CTSD (0.44) BACE1CTSDCALCRLRAMP1GLP1R
SCHEMBL29421924 0.84 APLNR (0.49) GLP1RGIPR
SCHEMBL29855903 0.84 NPY2R (0.53) GLP1RGIPRRAMP3CALCRNPY2R
SCHEMBL30933092 0.84 NAA50 (0.47) RAMP3CALCRNAA50
SCHEMBL30009448 0.83 BACE1 (0.50) BACE1CTSDCALCRLRAMP1RAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199793-A Preparation method and application of long-acting recombinant canine insulin fusion protein 广州源博医药科技有限公司 2023-06-02 — — CN claimed
EP-4218804-B1 USE OF MYOSTATIN INHIBITORS AND COMBINATION THERAPIES SCHOLAR ROCK INC (US) 2026-01-21 — — EP disclosed
CN-116199793-B Preparation method and application of long-acting recombinant canine insulin fusion protein 广州源博医药科技有限公司 2025-05-02 — — CN disclosed
WO-2025021915-A1 CD277 TARGETING COSTIMULATORY RECEPTOR UMC UTRECHT HOLDING B.V. (NL) 2025-01-30 — — WO disclosed
CN-114829585-B Composition for culturing T cells and method for culturing T cells using the same 吉爱希公司 2024-08-23 — — CN disclosed
US-20240270815-A1 Antigen Presenting Polypeptide Complexes and Methods of Use Thereof CUE BIOPHARMA, INC. 2024-08-15 — — US disclosed
CN-114276432-B Purification method of recombinant human insulin C peptide 鲁南制药集团股份有限公司 2024-07-23 — — CN disclosed
US-20240197846-A1 Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof CUE BIOPHARMA, INC. 2024-06-20 — — US disclosed
US-20240190933-A1 Antigen Presenting Polypeptide Complexes Bearing TGF-Beta and Methods of Use Thereof CUE BIOPHARMA, INC. 2024-06-13 — — US disclosed
EP-4346889-A2 ANTIGEN PRESENTING POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF Cue Biopharma, Inc. (US) 2024-04-10 — — EP disclosed
EP-4218804-A2 USE OF MYOSTATIN INHIBITORS AND COMBINATION THERAPIES Scholar Rock, Inc. (US) 2023-08-02 — — EP disclosed
WO-2022226054-A9 ANTIGEN PRESENTING POLYPEPTIDE COMPLEXES BEARING TGF-BETA AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. (US) 2023-07-27 — — WO disclosed
CN-116199793-A Preparation method and application of long-acting recombinant canine insulin fusion protein 广州源博医药科技有限公司 2023-06-02 — — CN disclosed
WO-2022251552-A2 ANTIGEN PRESENTING POLYPEPTIDE COMPLEXES AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. (US) 2022-12-01 — — WO disclosed
WO-2022226058-A1 ANTIGEN-PRESENTING POLYPEPTIDES WITH CHEMICAL CONJUGATION SITES AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. (US) 2022-10-27 — — WO disclosed
WO-2022226054-A2 ANTIGEN PRESENTING POLYPEPTIDE COMPLEXES BEARING TGF-BETA AND METHODS OF USE THEREOF CUE BIOPHARMA, INC. (US) 2022-10-27 — — WO disclosed
CN-114829585-A Composition for culturing T cells and method for culturing T cells using same 吉爱希公司 2022-07-29 — — CN disclosed
CN-114585373-A Precursor regulatory cytotrophoblast cells and uses thereof 艾克塞利瑞提德生物技术公司 2022-06-03 — — CN disclosed
CN-114466860-A Proinsulin peptides for type 1 diabetes 伦敦国王学院 2022-05-10 — — CN disclosed
CN-114276432-A Purification method of recombinant human insulin C peptide 鲁南制药集团股份有限公司 2022-04-05 — — CN disclosed
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