SCHEMBL29354292

SCHEMBL29354292

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OC[C@@H](O)[C@@H](O)[C@@H](O)C=O)[C@@H](O)[C@H]1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 7/20 0.77
P2RY2 P41231 3/20 0.77
P2RX1 P51575 2/20 0.77
P2RX3 P56373 2/20 0.77
ALDH1A1 P00352 2/20 0.77
SRC P12931 2/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
P2RX4 Q99571 1/20 0.77
P2RX2 Q9UBL9 1/20 0.77
TRPM2 O94759 2/20 0.72
MACROD2 A1Z1Q3 1/20 0.72
SIRT6 Q8N6T7 1/20 0.72
MACROD1 Q9BQ69 1/20 0.72
RNASEL Q05823 1/20 0.66
TAS1R3 Q7RTX0 2/20 0.66
TAS1R1 Q7RTX1 2/20 0.66
DNPH1 O43598 1/20 0.66
PRKAB2 O43741 1/20 0.66
LDHA P00338 1/20 0.66
ADRB2 P07550 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389326 0.99 P2RY1 (0.75) P2RY1P2RY2P2RX1P2RX3ALDH1A1
SCHEMBL22099721 0.93 P2RY1 (0.69) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL985843 0.93 P2RY1 (0.71) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Phosphate SCHEMBL2828289 0.92 P2RY1 (0.76) P2RY1P2RY2P2RX1P2RX3ALDH1A1
SCHEMBL32662848 0.92 RNASEL (0.68) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL27776323 0.92 P2RY1 (0.73) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL22498771 0.91 P2RY1 (0.72) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL30751027 0.91 P2RY1 (0.72) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL424711 0.91 P2RY1 (0.72) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine SCHEMBL21067523 0.91 P2RY2 (0.62) P2RY1P2RY2P2RX1P2RX3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 855 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4291664-B1 SITE-SPECIFIC GENOME MODIFICATION TECHNOLOGY UNIV NORTH CAROLINA STATE (US) 2026-05-27 EP claimed
WO-2026090321-A1 TREATMENT OF CANCER WITH A KRAS INHIBITOR ALTEROME THERAPEUTICS, INC. (US) 2026-04-30 WO claimed
EP-4731270-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR The Regents of The University of California (US) 2026-04-29 EP claimed
US-20260097020-A1 THERAPEUTIC USE OF AROMATASE INHIBITORS AND POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS FOR THE TREATMENT OF MALIGNANCIES UNIV CINCINNATI (US) 2026-04-09 US claimed
EP-4719372-A1 5-FU COMBINATIONS FOR USE IN TREATING ACTINIC KERATOSIS OR BASAL CELL CARCINOMA Alexandroff, Anton (GB) 2026-04-08 EP claimed
EP-4719373-A1 PHOTODYNAMIC THERAPY COMBINATIONS FOR IMPROVEMENT OF ACTINIC KERATOSIS, ACNE AND BASAL CELL CARCINOMA Alexandroff, Anton (GB) 2026-04-08 EP claimed
US-12564589-B2 Methods for treating cancer, reducing side effects of cancer treatment, and preventing the recurrence of cancer FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-03-03 US claimed
WO-2025245463-A9 COMBINATION THERAPIES MERCK PATENT GMBH (DE) 2025-12-26 WO claimed
WO-2025264823-A1 TREATMENT OF DISEASE METASHAPE PHARMA AG (CH) 2025-12-26 WO claimed
WO-2025245463-A1 COMBINATION THERAPIES MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
CN-115980169-A Use of mass spectrometry techniques for identifying muscle biomarkers 中国科学院动物研究所 2023-04-18 CN claimed
CN-114042160-B CTD-2256P15.2 and application of encoded micro-peptide thereof as target in development of tumor treatment drugs 中国科学院动物研究所 2023-04-14 CN claimed
WO-2022245922-A1 POLY-ADP RIBOSE (PAR) TRACKER OPTIMIZED SPLIT-PROTEIN REASSEMBLY PAR DETECTION REAGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-11-24 WO claimed
WO-2022233782-A1 COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION LEAD DISCOVERY CENTER GMBH (DE) 2022-11-10 WO claimed
WO-2022225995-A1 METHODS AND SYSTEMS FOR GENE ALTERATION PREDICTION FROM PATHOLOGY SLIDE IMAGES F. HOFFMANN-LA ROCHE AG (CH) 2022-10-27 WO claimed
US-11480568-B2 Diagnosis of autoimmune diseases YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-10-25 US claimed
US-11459597-B2 Methods for the design of mechanism-based sirtuin activating compounds CHAKRABARTI ADVANCED TECHNOLOGY LLC (US) 2022-10-04 US claimed
WO-2022174144-A1 SITE-SPECIFIC GENOME MODIFICATION TECHNOLOGY NORTH CAROLINA STATE UNIVERSITY (US) 2022-08-18 WO claimed
US-20220072167-A1 Methods for Treating Cancer Using Combinations of PARP Inhibitors and Antibody Radioconjugates ACTINIUM PHARMACEUTICALS, INC. (US) 2022-03-10 US claimed
WO-2022020359-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING HIGH GRADE SUBTYPES OF UTERINE CANCER THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-01-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564589-B2 Methods for treating cancer, reducing side effects of cancer treatment, and preventing the recurrence of cancer BRCA1, PARP1, PARP2 P2RY1 1722/4885P2RY2 1433/4885P2RX1 2256/4885
US-20260097020-A1 THERAPEUTIC USE OF AROMATASE INHIBITORS AND POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS FOR THE TREATMENT OF MALIGNANCIES PARP2, PARP12, PARP1 P2RY1 306/4885P2RY2 138/4885P2RX1 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.