SCHEMBL29354331

SCHEMBL29354331

CSc1nc(O)c(C(=O)Nc2ccc(-c3c[nH]nn3)cc2F)c(=O)[nH]1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
XDH P47989 20/20 0.71
SLC22A12 Q96S37 6/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20915788 1.00 XDH (0.71) XDHSLC22A12
SCHEMBL20915723 0.90 XDH (0.73) XDHSLC22A12
SCHEMBL20915794 0.89 XDH (0.71) XDHSLC22A12
SCHEMBL20915821 0.88 XDH (0.73) XDHSLC22A12
SCHEMBL20915776 0.88 XDH (0.70) XDHSLC22A12
SCHEMBL20915875 0.87 XDH (0.75) XDHSLC22A12
SCHEMBL20915685 0.87 XDH (0.75) XDHSLC22A12
SCHEMBL20915862 0.86 XDH (0.73) XDHSLC22A12
SCHEMBL20915730 0.86 XDH (0.75) XDHSLC22A12
SCHEMBL20915816 0.86 XDH (0.71) XDHSLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476642-B Compounds and their use for reducing uric acid levels 阿奎斯特有限责任公司 2022-01-25 CN disclosed