SCHEMBL29354543

SCHEMBL29354543

COCOc1cc2c(N3CCC(C(C)CN)CC3)ccnc2cc1OC

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 1/20 0.53
EHMT2 Q96KQ7 7/20 0.51
EHMT1 Q9H9B1 7/20 0.51
ENPP1 P22413 2/20 0.44
FLT3 P36888 1/20 0.42
PDGFRB P09619 1/20 0.40
NPC1 O15118 1/20 0.39
HTR1A P08908 1/20 0.39
HTR7 P34969 1/20 0.39
PDE3B Q13370 3/20 0.39
PDE3A Q14432 3/20 0.39
PDE10A Q9Y233 3/20 0.39
MAPK1 P28482 1/20 0.39
NTSR1 P30989 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22441468 1.00 NCF1 (0.53) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL22445589 1.00 NCF1 (0.53) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL22441558 0.94 NCF1 (0.59) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL22445487 0.94 NCF1 (0.59) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL22441473 0.91 EHMT2 (0.55) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL22445583 0.91 EHMT2 (0.55) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL29354516 0.91 EHMT2 (0.55) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL22445672 0.90 NCF1 (0.57) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL22441454 0.85 NCF1 (0.52) NCF1EHMT2EHMT1ENPP1FLT3
SCHEMBL29357502 0.85 NCF1 (0.52) NCF1EHMT2EHMT1ENPP1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113924092-B Quinoline and quinazoline compounds and methods of use thereof 斯汀格瑞治疗股份有限公司 2025-03-18 CN disclosed
EP-3941459-A1 QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF Stingray Therapeutics, Inc. (US) 2022-01-26 EP disclosed