Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 4/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510271 | 0.85 | EGFR (0.47) | EGFRALDH1A1GFERKDM4ERAB9A | |
| SCHEMBL20025790 | 0.78 | CYP3A4 (0.55) | EGFRALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL30465526 | 0.78 | ALDH1A1 (0.43) | EGFRALDH1A1GFERKDM4ERAB9A | |
| SCHEMBL31506725 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL2171531 | 0.73 | TDP1 (0.58) | HPGDSTDP1 | |
| SCHEMBL28628097 | 0.73 | MEN1 (0.56) | ALDH1A1KMT2AMEN1CYP1A2NCF1 | |
| SCHEMBL27947003 | 0.73 | ALDH1A1 (0.50) | EGFRALDH1A1GFERKDM4ERAB9A | |
| SCHEMBL202174 | 0.72 | ALDH1A1 (0.47) | EGFRALDH1A1GFERKDM4ERAB9A | |
| SCHEMBL15221601 | 0.72 | TP53 (0.42) | EGFRALDH1A1GFERKDM4ERAB9A | |
| SCHEMBL2245058 | 0.71 | SLC6A2 (0.54) | HPGDSTDP1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |