Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPER1 | Q99527 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394793 | 1.00 | GPER1 (0.51) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL21394805 | 0.93 | ABL1 (0.44) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL29358195 | 0.93 | ABL1 (0.44) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL29353818 | 0.89 | ABL1 (0.57) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL21394850 | 0.89 | ABL1 (0.57) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL21395007 | 0.87 | RAB9A (0.59) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL21394882 | 0.85 | SCD (0.52) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL29353798 | 0.85 | SCD (0.52) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL21394797 | 0.85 | SCD (0.49) | GPER1ABL1RAB9AALDH1A1LMNA | |
| SCHEMBL21394530 | 0.84 | SCD (0.51) | GPER1ABL1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |