SCHEMBL29355223

SCHEMBL29355223

O=C(CCSSc1ccccn1)NCCCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.42
HDAC1 Q13547 6/20 0.37
HDAC2 Q92769 6/20 0.37
HDAC3 O15379 3/20 0.37
HDAC4 P56524 3/20 0.37
HDAC7 Q8WUI4 3/20 0.37
HDAC10 Q969S8 3/20 0.37
HDAC11 Q96DB2 3/20 0.37
HDAC8 Q9BY41 3/20 0.37
HDAC6 Q9UBN7 3/20 0.37
HDAC9 Q9UKV0 3/20 0.37
HDAC5 Q9UQL6 3/20 0.37
ALDH1A1 P00352 5/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
KDM4E B2RXH2 3/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43173 1.00 HPGD (0.42) HPGDHDAC1HDAC2HDAC3HDAC4
SCHEMBL31005444 1.00 HPGD (0.42) HPGDHDAC1HDAC2HDAC3HDAC4
SCHEMBL14273419 0.96 HPGD (0.43) HPGDHDAC1HDAC2ALDH1A1SMN1; SMN2
SCHEMBL31005443 0.96 HPGD (0.43) HPGDHDAC1HDAC2ALDH1A1SMN1; SMN2
SCHEMBL29201024 0.94 HPGD (0.39) HPGDHDAC1HDAC2HDAC3HDAC4
SCHEMBL18510191 0.92 HPGD (0.45) HPGDHDAC1HDAC2ALDH1A1SMN1; SMN2
SCHEMBL18510177 0.92 HPGD (0.45) HPGDHDAC1HDAC2ALDH1A1SMN1; SMN2
SCHEMBL18519268 0.92 HPGD (0.45) HPGDHDAC1HDAC2ALDH1A1SMN1; SMN2
SCHEMBL18510194 0.91 HPGD (0.44) HPGDHDAC1HDAC2ALDH1A1SMN1; SMN2
SCHEMBL18510196 0.91 HPGD (0.44) HPGDHDAC1HDAC2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719485-A1 ANTIBODY-DRUG CONJUGATES FOR TREATING INFECTIONS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) Taimed Biologics Inc. (TW) 2026-04-08 EP claimed
EP-4716755-A1 RNA PROBING AND AMPLIFICATION METHODS FOR SINGLE CELL ANALYSIS ON FIXED CELLS Becton, Dickinson and Company (US) 2026-04-01 EP claimed
US-12578320-B2 Methods and systems for physical expansion and imaging of biological samples YALE UNIVERSITY (US) 2026-03-17 US claimed
WO-2025235971-A1 METHODS FOR DETECTING DNA SEQUENCE VARIATION IN THICK TISSUE SECTIONS THE JOHNS HOPKINS UNIVERSITY (US) 2025-11-13 WO claimed
EP-4642491-A1 METHOD FOR GLYCOPROTEIN MODIFICATION Honeybear Biosciences Inc. (TW) 2025-11-05 EP claimed
US-20250295745-A1 CROSS-LINKED TUMOR LYSATE SPHERICAL NUCLEIC ACIDS AS CANCER VACCINES NORTHWESTERN UNIVERSITY 2025-09-25 US claimed
EP-4615969-A1 METHODS FOR DETECTING RNA AND MOLECULAR ANALYSIS IN THICK TISSUE SECTIONS The Johns Hopkins University (US) 2025-09-17 EP claimed
US-12330138-B2 Surface functionalised materials for sampling biological molecules JONES, Paul Antonio (GB) 2025-06-17 US claimed
EP-3765188-B1 SURFACE FUNCTIONALISED MATERIALS FOR SAMPLING BIOLOGICAL MOLECULES JONES PAUL ANTONIO (GB) 2025-04-16 EP claimed
CN-112533640-B Targeting of M2-type tumor-associated macrophages using melittin-based apoptosis-inducing peptides 双亥生命科学株式会社 2025-02-28 CN claimed
EP-4117820-A1 METHODS AND SYSTEMS FOR PHYSICAL EXPANSION AND IMAGING OF BIOLOGICAL SAMPLES Yale University (US) 2023-01-18 EP claimed
CN-115551638-A Method and system for physical expansion and imaging of biological samples 耶鲁大学 2022-12-30 CN claimed
EP-4103744-A2 INTRACELLULAR ABSEQ Becton, Dickinson and Company (US) 2022-12-21 EP claimed
EP-4103585-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF Twinpig Biolab, Inc. (KR) 2022-12-21 EP claimed
US-20220354957-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF TWINPIG BIOLAB, INC. (KR) 2022-11-10 US claimed
WO-2022234346-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF TWINPIG BIOLAB, INC. (KR) 2022-11-10 WO claimed
US-11484601-B2 Targeting M2-like tumor-associated macrophages by using melittin-based proapoptotic peptide TWINPIGBIOLAB INC. (KR) 2022-11-01 US claimed
CN-115087746-A Intracellular AbSeq 贝克顿迪金森公司 2022-09-20 CN claimed
WO-2022129926-A1 IMPROVED CELL-PENETRATING PEPTIDES AND FUSION PROTEINS ANASTASIS BIOTEC LIMITED (GB) 2022-06-23 WO claimed
US-11332880-B2 Modifying natural feathers for use in sporting goods DURABIRD (US) 2022-05-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12578320-B2 Methods and systems for physical expansion and imaging of biological samples KRT18, DSP, SMCHD1 HPGD 4825/4885HDAC1 2380/4885HDAC2 3179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.