SCHEMBL29355263

SCHEMBL29355263

COc1ccc(-c2cc(C)nn2-c2ccc(S(N)(=O)=O)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 15/20 0.73
PTGS1 P23219 7/20 0.73
CA1 P00915 4/20 0.71
CA2 P00918 4/20 0.71
CA9 Q16790 4/20 0.71
CHRNA7 P36544 1/20 0.67
ALOX5 P09917 2/20 0.57
PTGES O14684 1/20 0.57
HDAC3 O15379 1/20 0.57
PDPK1 O15530 1/20 0.57
CA12 O43570 1/20 0.57
PDE5A O76074 1/20 0.57
ABCB11 O95342 1/20 0.57
MT-CO2 P00403 1/20 0.57
LMNA P02545 1/20 0.57
CA3 P07451 1/20 0.57
CYP3A4 P08684 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216745 0.88 PTGS2 (0.89) PTGS2PTGS1CA1CA2CA9
SCHEMBL2602400 0.87 PTGS2 (0.80) PTGS2PTGS1CA1CA2CA9
SCHEMBL5698606 0.85 PTGS2 (0.76) PTGS2PTGS1CHRNA7PDPK1
SCHEMBL5698671 0.85 PTGS2 (0.76) PTGS2PTGS1CHRNA7PDPK1
SCHEMBL2615132 0.85 PTGS2 (0.76) PTGS2PTGS1CA1CA2CA9
SCHEMBL16888132 0.84 PTGS2 (0.60) PTGS2PTGS1CA1CA2CA9
SCHEMBL213569 0.84 PTGS2 (1.00) PTGS2PTGS1CA1CA2CA9
SCHEMBL6340846 0.84 PTGS2 (0.75) PTGS2PTGS1CA1CA2CA9
SCHEMBL6350879 0.84 PTGS2 (1.00) PTGS2PTGS1CA1CA2CA9
SCHEMBL5226958 0.84 PTGS2 (1.00) PTGS2PTGS1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114452669-B Reclaimed material liquid rectifying and purifying system containing NMP 派尔森环保科技有限公司 2023-05-19 CN claimed
CN-114452669-A NMP-containing feed liquid recycling, rectifying and purifying system 派尔森环保科技有限公司 2022-05-10 CN claimed
US-11902616-B2 Audio-visual device D&M HOLDINGS, INC. (JP) 2024-02-13 US disclosed
CN-117451092-A Vehicle-mounted sensor calibration method, system, electronic device and storage medium 大连理工大学 2024-01-26 CN disclosed
CN-117321631-A SLAM guided monocular depth improvement system using self-supervised online learning 创峰科技 2023-12-29 CN disclosed
CN-116745813-A Self-supervision type depth estimation framework for indoor environment 创峰科技 2023-09-12 CN disclosed
CN-109903343-B Feature matching method based on inertial attitude constraint 东南大学 2023-05-23 CN disclosed
CN-114452669-B Reclaimed material liquid rectifying and purifying system containing NMP 派尔森环保科技有限公司 2023-05-19 CN disclosed
EP-3522551-B1 AUDIO/VIDEO DEVICE D & M HOLDINGS INC (JP) 2023-05-10 EP disclosed
CN-114452669-A NMP-containing feed liquid recycling, rectifying and purifying system 派尔森环保科技有限公司 2022-05-10 CN disclosed
US-20220121539-A1 AUDIO-VISUAL DEVICE D&M HOLDINGS, INC. (JP) 2022-04-21 US disclosed
US-11234045-B2 Audio-visual device D&M HOLDINGS, INC. (JP) 2022-01-25 US disclosed