SCHEMBL29355273

SCHEMBL29355273

CC(C)(C)c1ccccc1C(C)(C)C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
TDP1 Q9NUW8 2/20 0.63
TSHR P16473 2/20 0.63
CA2 P00918 3/20 0.58
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
KIF11 P52732 1/20 0.44
ALOX15 P16050 2/20 0.40
CYP1A2 P05177 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
ATP2A2 P16615 1/20 0.40
ATP2A3 Q93084 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
ALOX12 P18054 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TYR P14679 2/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580584 1.00 ALDH1A1 (0.63) ALDH1A1TDP1TSHRCA2GABRA1
Methyl Alcohol SCHEMBL28457865 0.93 ALDH1A1 (0.65) ALDH1A1TDP1TSHRCA2GABRA1
Bromomethane SCHEMBL28461678 0.93 ALDH1A1 (0.57) ALDH1A1TDP1TSHRCA2GABRA1
Hydrochloric Acid SCHEMBL31147078 0.93 ALDH1A1 (0.57) ALDH1A1TDP1TSHRCA2GABRA1
Methylamine SCHEMBL28294592 0.93 ALDH1A1 (0.57) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL28606377 0.90 ALDH1A1 (0.55) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL6281520 0.90 ALDH1A1 (0.55) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL9149883 0.90 ALDH1A1 (0.55) ALDH1A1TDP1TSHRCA2GABRA1
Methoxymethane SCHEMBL28022478 0.90 ALDH1A1 (0.55) ALDH1A1TDP1TSHRCA2GABRA1
SCHEMBL29134245 0.87 ALDH1A1 (0.59) ALDH1A1TDP1TSHRCA2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853389-A Preparation method of low-temperature recycled asphalt and mixture 遂宁天孜路新材料技术有限公司 2022-08-05 CN claimed
CN-113969011-A Low-temperature-resistant crosslinked polyethylene material and preparation method thereof 江南大学 2022-01-25 CN claimed
US-20260077278-A1 AROMATIC EUTECTIC MIXTURES AND THEIR USE AS SOLVENTS, PARTICULARLY IN LIQUID-LIQUID SEPARATION COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2026-03-19 US disclosed
US-20260079271-A1 AROMATIC EUTECTIC MIXTURES AND THEIR USE AS LIQUID SCINTILLATORS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2026-03-19 US disclosed
CN-117616055-A Polyethylene copolymers with broad short chain branching distribution 格雷斯公司 2024-02-27 CN disclosed
CN-114853389-A Preparation method of low-temperature recycled asphalt and mixture 遂宁天孜路新材料技术有限公司 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077278-A1 AROMATIC EUTECTIC MIXTURES AND THEIR USE AS SOLVENTS, PARTICULARLY IN LIQUID-LIQUID SEPARATION AHR, CYP1B1, ALK ALDH1A1 252/4885TDP1 223/4885TSHR 751/4885
US-20260079271-A1 AROMATIC EUTECTIC MIXTURES AND THEIR USE AS LIQUID SCINTILLATORS AHR, EWSR1, CBX3 ALDH1A1 785/4885TDP1 276/4885TSHR 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.