SCHEMBL29355355

SCHEMBL29355355

FC(F)(F)c1cccc(CBr)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.60
IDO1 P14902 2/20 0.58
HTR2A P28223 2/20 0.56
HTR2B P41595 2/20 0.56
HTR2C P28335 1/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
ACP3 P15309 1/20 0.55
MIF P14174 2/20 0.53
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
GAA P10253 1/20 0.51
MAOB P27338 3/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
SIGMAR1 Q99720 1/20 0.49
ADRA2C P18825 1/20 0.49
SLC6A4 P31645 1/20 0.49
ADRA1A P35348 1/20 0.49
DRD3 P35462 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4567 1.00 TAAR1 (0.60) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL11027533 0.98 TAAR1 (0.58) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL2008094 0.98 TAAR1 (0.58) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL10269861 0.88 MAOB (0.53) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL2647549 0.86 MEN1 (0.52) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL6354530 0.84 CETP (0.48) TAAR1IDO1MEN1KMT2AKDM4E
SCHEMBL177514 0.83 TAAR1 (0.67) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL30186510 0.83 TAAR1 (0.67) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL3283996 0.83 TAAR1 (0.43) TAAR1IDO1HTR2AHTR2BHTR2C
SCHEMBL5103155 0.82 TAAR1 (0.64) TAAR1IDO1HTR2AHTR2BHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055361-A Fascin inhibitors 北京双鹤润创科技有限公司 2026-05-15 CN disclosed
EP-4739669-A1 SODIUM CHANNEL BLOCKERS Novartis AG (CH) 2026-05-13 EP disclosed
EP-4720054-A1 FASCIN INHIBITORS Beijing Double-Crane Runchuang Technology Co., Ltd. (CN) 2026-04-08 EP disclosed
WO-2025129168-A1 TRIAZOLONE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE AND THEIR THERAPEUTIC USES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-06-19 WO disclosed
EP-4561561-A2 SUBSTITUTED 3,4-DIHYDROQUINOLINONE INHIBITORS OF TSHR Septerna, Inc. (US) 2025-06-04 EP disclosed
CN-119998288-A Hydantoin modulators of cholesterol biosynthesis and their use for promoting remyelination 基因泰克公司 2025-05-13 CN disclosed
CN-119954725-A TEAD inhibitors and uses thereof 医肯纳肿瘤学公司 2025-05-09 CN disclosed
CN-119894866-A YAP/TAZ-TEAD oncoprotein inhibitors 布里奇恩生物科学公司 2025-04-25 CN disclosed
CN-119497709-A Pyrimidine derivatives ASKA 制药株式会社 2025-02-21 CN disclosed
CN-119487006-A Amide compounds as PGE2 receptor antagonists 广东新契生物医药科技有限公司 2025-02-18 CN disclosed
CN-114650992-A GPR52 modulator compounds 赫普泰雅治疗有限公司 2022-06-21 CN disclosed
CN-114524776-A Tetrazole compound and application thereof 中国科学院广州生物医药与健康研究院 2022-05-24 CN disclosed
CN-114466839-A TEAD inhibitors and uses thereof 医肯纳肿瘤学公司 2022-05-10 CN disclosed
WO-2022076627-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-04-14 WO disclosed
EP-3976192-A1 TEAD INHIBITORS AND USES THEREOF Ikena Oncology, Inc. (US) 2022-04-06 EP disclosed
CN-114206861-A Fused heteroaryl compounds useful as RIPK1 inhibitors 比西切姆有限公司 2022-03-18 CN disclosed
CN-114174273-A Compounds and uses thereof 优曼尼蒂治疗公司 2022-03-11 CN disclosed
WO-2022043714-A1 GPR52 MODULATOR COMPOUNDS HEPTARES THERAPEUTICS LIMITED (GB) 2022-03-03 WO disclosed
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed
EP-3941908-A1 COMPOUNDS AND USES THEREOF Yumanity Therapeutics, Inc. (US) 2022-01-26 EP disclosed