Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | ACP3 | P15309 | 1/20 | 0.58 |
| ▸ | MIF | P14174 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3602086 | 0.98 | TAAR1 (0.62) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL2124663 | 0.98 | IDO1 (0.63) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL2093444 | 0.86 | TAAR1 (0.60) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL3237564 | 0.86 | TAAR1 (0.64) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL46757 | 0.84 | HTR2A (0.63) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL3643679 | 0.84 | TAAR1 (0.62) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| Pivalate SCHEMBL9952824 | 0.84 | ACP3 (0.53) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL41778 | 0.82 | TAAR1 (0.60) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL7452386 | 0.82 | TAAR1 (0.60) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL14423479 | 0.82 | TAAR1 (0.60) | TAAR1IDO1HTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108174603-B | 1-heteroaryl-indoline-4-carboxamides as GPR52 modulators | 阿芮纳制药有限公司 | 2021-07-02 | — | — | CN | disclosed |
| US-20080021026-A1 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | Kahraman, Mehmet (US) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021026-A1 | BENZOTHIOPHENE INHIBITORS OF RHO KINASE | RHOT2, ROCK2, ROCK1 | TAAR1 4416/4885IDO1 3541/4885HTR2A 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.