Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395036 | 1.00 | RAB9A (0.42) | RAB9ARIPK1EP300IDH1AURKA | |
| SCHEMBL21394752 | 0.88 | RAB9A (0.41) | RAB9ARIPK1EP300 | |
| SCHEMBL29356890 | 0.88 | RAB9A (0.41) | RAB9ARIPK1EP300 | |
| SCHEMBL29356885 | 0.88 | RAB9A (0.41) | RAB9ARIPK1EP300SIRT2F10 | |
| SCHEMBL21395110 | 0.88 | RAB9A (0.41) | RAB9ARIPK1EP300SIRT2F10 | |
| SCHEMBL22479693 | 0.87 | RAB9A (0.45) | RAB9AF10PARP1 | |
| SCHEMBL21395053 | 0.86 | RAB9A (0.44) | RAB9AF10PARP1 | |
| SCHEMBL21394559 | 0.86 | RAB9A (0.44) | RAB9APARP1 | |
| SCHEMBL21394773 | 0.86 | RAB9A (0.44) | RAB9AF10PARP1 | |
| SCHEMBL29358581 | 0.86 | RAB9A (0.44) | RAB9APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |