Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CSNK2A2 | P19784 | 12/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | BCL6 | P41182 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30279843 | 0.99 | KDM4E (0.60) | KDM4EALDH1A1CSNK2A2CSNK2A1HPGD | |
| Trifluoroacetic Acid SCHEMBL30279847 | 0.88 | BCL6 (0.51) | KDM4EALDH1A1CSNK2A2CSNK2A1HPGD | |
| SCHEMBL15288758 | 0.78 | CDK2 (0.64) | CSNK2A2CSNK2A1BCL6CDK2CSNK2B | |
| SCHEMBL1935284 | 0.74 | CSNK2B (0.61) | KDM4EALDH1A1CSNK2A2CSNK2A1BCL6 | |
| SCHEMBL30279846 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1CSNK2A2CSNK2A1HPGD | |
| SCHEMBL29352517 | 0.74 | CSNK2A2 (0.38) | KDM4EALDH1A1CSNK2A2CSNK2A1 | |
| SCHEMBL172459 | 0.73 | KDM4E (0.60) | KDM4EALDH1A1CSNK2A1HPGDCLK4 | |
| SCHEMBL30279842 | 0.73 | CSNK2A1 (0.58) | KDM4EALDH1A1CSNK2A2CSNK2A1HPGD | |
| SCHEMBL17502116 | 0.73 | CSNK2A1 (1.00) | CSNK2A2CSNK2A1BCL6CDK2CSNK2B | |
| SCHEMBL26621936 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1CSNK2A1HPGDCLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562111-B | CK2 inhibitors, compositions and methods thereof | 北极星药业股份有限公司 | 2023-04-04 | — | — | CN | claimed |
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | claimed |
| CN-109562111-B | CK2 inhibitors, compositions and methods thereof | 北极星药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | disclosed |