SCHEMBL29355778

SCHEMBL29355778

COc1cccc(Nc2nc(F)nc3[nH]cnc23)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SYK P43405 1/20 0.53
GRM4 Q14833 1/20 0.51
SRC P12931 2/20 0.47
AURKA O14965 1/20 0.47
CYP1A2 P05177 1/20 0.46
MEN1 O00255 2/20 0.46
MAPK1 P28482 2/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46
LRRK2 Q5S007 2/20 0.45
CSNK2A1 P68400 1/20 0.45
DYRK3 O43781 1/20 0.45
MAP4K4 O95819 1/20 0.45
EGFR P00533 1/20 0.45
PDGFRA P16234 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2991717 1.00 HTT (0.54) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL2998386 0.86 NPC1 (0.55) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL3004036 0.85 NPC1 (0.54) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL30719583 0.85 NPC1 (0.54) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL3006445 0.85 EGFR (0.56) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL30162946 0.85 EGFR (0.56) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL3003946 0.83 NPC1 (0.49) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL30572212 0.82 NPC1 (0.69) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL30496805 0.82 NPC1 (0.69) HTTNPC1RAB9ALMNASMN1; SMN2
SCHEMBL2991721 0.82 NPC1 (0.69) HTTNPC1RAB9ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680598-A1 4-DIFLUOROMETHYL BENZAMIDES WITH HERBICIDAL ACTION Bayer Aktiengesellschaft (DE) 2026-01-21 EP disclosed
EP-4655284-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-12-03 EP disclosed
EP-4626882-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-10-08 EP disclosed
EP-4618745-A1 USE OF ISOTIANIL FOR CONTROLLING PLASMODIOPHORA BRASSICA Bayer Aktiengesellschaft (DE) 2025-09-24 EP disclosed
EP-4619396-A1 MICROBIOCIDAL TETRAHYDROISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-09-24 EP disclosed
EP-4615829-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-09-17 EP disclosed
EP-4605379-A1 BROMINE- OR IODINE-PARA-SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND SALTS THEREOF, PROTECTION AGENTS COMPRISING THEM, FOR USEFUL PLANTS OR CROP PLANTS, METHODS FOR PRODUCING THEM AND USE THEREOF AS SAFENERS Bayer Aktiengesellschaft (DE) 2025-08-27 EP disclosed
EP-4602036-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2025-08-20 EP disclosed
EP-4594311-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-08-06 EP disclosed
EP-4594310-A1 MICROBIOCIDAL PYRAZOLE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-08-06 EP disclosed
CN-114450280-A Pesticidally active heterocyclic derivatives with sulphur-and sulphoxide imine substituents 先正达农作物保护股份公司 2022-05-06 CN disclosed
CN-114401963-A Pesticidally active cyclic amine compounds 先正达农作物保护股份公司 2022-04-26 CN disclosed
CN-114341142-A Strigolactone derivatives as plant growth regulator compounds 先正达农作物保护股份公司 2022-04-12 CN disclosed
EP-3976601-A1 MICROBIOCIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2022-04-06 EP disclosed
EP-3976586-A1 MICROBIOCIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2022-04-06 EP disclosed
EP-3976622-A1 MICROBIOCIDAL DERIVATIVES Syngenta Crop Protection AG (CH) 2022-04-06 EP disclosed
CN-114269732-A Pesticidally active pyrazine-amide compounds 先正达农作物保护股份公司 2022-04-01 CN disclosed
CN-114072384-A Microbicidal picolinamide derivatives 先正达农作物保护股份公司 2022-02-18 CN disclosed
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP disclosed
CN-113966171-A Fungicidal compositions 先正达农作物保护股份公司 2022-01-21 CN disclosed